Extending reliability to intensive longitudinal data with the Kalman filter
Abstract Reliability is central to how researchers approach measurement in standard, group‐based analyses of single‐time‐point data, yet this critical aspect is often overlooked in the analysis of repeated observations. Since its inception, reliability has been a between‐person concept, but we redevelop this notion for within‐person designs by ...
Michael D. Hunter
wiley +1 more source
SUSD2 Promotes Metastasis and Primary Tumor Growth in Pancreatic Cancer Cells via Integrin-FAK Signaling Activation. [PDF]
Yoshida J +11 more
europepmc +1 more source
Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source
Dynamic Factor Analysis for Sparse and Irregular Longitudinal Data: An Application to Metabolite Measurements in a COVID-19 Study. [PDF]
Cai J, Goudie RJB, Tom BDM.
europepmc +1 more source
OncoVV‑shHSP70, a vaccinia virus silencing HSP70, demonstrated potent antitumor efficacy in colorectal cancer cell lines, as well as in syngeneic, xenograft, and humanized mouse models. In cell lines, oncoVV‑shHSP70 promoted viral oncolysis and cytokine production through a self‑reinforcing cycle of ROS‑autophagy. In both CT26 and SW620‑humanized mouse
Rentao Yuan +8 more
wiley +1 more source
Safety and feasibility of talimogene laherparepvec in peritoneal surface malignancies: Results from the TEMPO trial. [PDF]
Stewart JH +10 more
europepmc +1 more source
Environmentally adjusted productivity growth and shadow prices for dairy farms
Abstract We estimate the environmentally adjusted productivity growth and shadow price for Ontario dairy farms. We use an input‐oriented directional distance function and farm‐level data from 2000 to 2020. First, we find that while GHG emissions per cow increase with higher milk yields, emission intensity decreases as milk yield per cow increases.
Bibek Dahal +2 more
wiley +1 more source
A new strategy for melanoma treatment: an investigation of the clinical value of the combination of immune checkpoint inhibitors and oncolytic viruses. [PDF]
Sui B, Jin X, Zheng X.
europepmc +1 more source
Abstract One of the most contentious issues in the study of the Atlantic slave trade is the profitability of the trade. In this paper, we contribute by pooling all available data on transatlantic slave ship voyage accounts into a joint dataset. This dataset includes data from a period of 100 years (1730–1830) and from five nations (Denmark, France ...
Klas Rönnbäck +4 more
wiley +1 more source
Advancements in intratumoral therapies for liver tumors. [PDF]
Raman SS +7 more
europepmc +1 more source

