Results 91 to 100 of about 69,236 (249)
Carolyn L. Hodo +4 more
openaire +2 more sources
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen +5 more
wiley +1 more source
Immune complexes in chronic Chagas disease patients are formed by exovesicles from Trypanosoma cruzi carrying the conserved MASP N-terminal region [PDF]
The exovesicles (EVs) are involved in pathologic host-parasite immune associations and have been recently used as biomarkers for diagnosis of infectious diseases.
De Pablos, Luis Miguel +5 more
core +3 more sources
ABSTRACT Porcelia macrocarpa is a Brazilian plant species belonging to the Annonaceae family. To date, more than 190 compounds have been identified and/or isolated from this species, with terpenoids comprising the majority (62%). Alkaloids represent the second most abundant class (11%), followed by steroids (4%), acetogenins (4%), fatty acids (4 ...
Fernanda Thevenard +4 more
wiley +1 more source
Interaction of Trypanosoma cruzi, Triatomines and the Microbiota of the Vectors—A Review
This review summarizes the interactions between Trypanosoma cruzi, the etiologic agent of Chagas disease, its vectors, triatomines, and the diverse intestinal microbiota of triatomines, which includes mutualistic symbionts, and highlights open questions.
Günter A. Schaub
doaj +1 more source
BackgroundVector-borne transmission of Trypanosoma cruzi is seen exclusively in the Americas where an estimated 8 million people are infected with the parasite. Significant research in southern Peru has been conducted to understand T. cruzi infection and
Karen A Alroy +16 more
doaj +1 more source
Frequency of the Congenital Transmission of Trypanosoma cruzi: A Systematic Review and Meta-Analysis [PDF]
BACKGROUND: Chagas disease is caused by the parasite Trypanosoma cruzi and is endemic in much of Latin America. With increased globalisation and immigration, it is a risk in any country, partly through congenital transmission. The frequency of congenital
Buekens, Pierre +4 more
core +1 more source
In vitro trypanocidal activity of a polyprenylated benzophenone‐enriched Brazilian red propolis extract (SEBz) and its major constituents, guttiferone E/xanthochymol (GUT/XAN) and oblongifolin B (OBL), exhibit in vitro trypanocidal activity against Trypanosoma cruzi, inducing ultrastructural damage with moderate cytotoxicity and no significant ...
Nicoli Dias Oliveira +9 more
wiley +1 more source
Chagas disease, caused by Trypanosoma cruzi, remains a serious public health problem worldwide. The parasite was subdivided into six distinct genetic groups, called “discrete typing units” (DTUs), from TcI to TcVI. Several studies have indicated that the
Marina Malheiros Araújo Silvestrini +9 more
doaj +1 more source
Detection of Trypanosoma cruzi in white-eared opossums (Didelphis albiventris) from Canoinhas, Santa Catarina State, Brazil [PDF]
Opossums are synanthropic animals that participate in the zoonotic transmission cycles. Chagas disease, a neglected tropical disease caused by Trypanosoma cruzi, affects many domestic and wild animals and humans worldwide.
Giane Helenita Pontarolo +10 more
doaj +1 more source

