Results 61 to 70 of about 17,578 (215)

Harnessing Natural Diversity and Rational Design for Enhanced Plant Immunity

Plant, Cell &Environment, Volume 49, Issue 11, Page 8643-8656, November 2026.
ABSTRACT Plant pathogens cause crop loss. Genetic resistance, through natural genetic diversity or engineered resistance, can be highly effective in protecting plants from infection. Genetic resistance from wild relatives of crops has been successfully introduced into crops to control pathogen infection.
Nathan Diplock, Jennifer D. Lewis
wiley   +1 more source

T3SS-based injection of transcription factors into hESC.

, 2018
(A) hESCs were co-cultured with strain Δ8 containing indicated ExoS54-TF fusions at indicated MOI (0, 30 or 150) for 3 hours. Cells were lysed, nuclear protein extracted and examined for injected proteins by anti-Flag immunoblot.
Zhenpeng Li (553533), Jing Shi (16730), Yongxin Jin (533449), Weihui Wu (533451), Katherine Santostefano (5007797), Shouguang Jin (255121), Ying Liu (18461), Zhihui Cheng (296359), Naohiro Terada (209817), Fang Bai (1612534), Xinwen Zhang (485325), Donghai Wu (309245)   +11 more
core   +1 more source

Regulation of the Pseudomonas syringae Type III Secretion System by Host Environment Signals

Microorganisms, 2021
Pseudomonas syringae are Gram-negative, plant pathogenic bacteria that use a type III secretion system (T3SS) to disarm host immune responses and promote bacterial growth within plant tissues. Despite the critical role for type III secretion in promoting
Megan R. O’Malley, Jeffrey C. Anderson
doaj   +1 more source

Nuclear importin α1 AtIMPA1 regulates stomatal reopening to defend against Pst DC3000 by orchestrating ABA signaling

The Plant Journal, Volume 128, Issue 3, November 2026.
SUMMARY Importin α family proteins serve as essential carriers for transporting specific disease‐resistant proteins into the nucleus, enabling these proteins to function properly. However, whether importin α proteins are involved in plant immunity remains unclear.
Ting Zhang, Kang Wang, Yi Guan, Jingao Zhang, Charles Tetteh, Chenxi Liu, Cheng Zhang, Pinyuan Jin, Sheng Luo, Yiling Wang, Huajian Zhang   +10 more
wiley   +1 more source

Increased plasmid copy number is essential for Yersinia T3SS function and virulence. [PDF]

, 2016
Pathogenic bacteria have evolved numerous virulence mechanisms that are essential for establishing infections. The enterobacterium Yersinia uses a type III secretion system (T3SS) encoded by a 70-kilobase, low-copy, IncFII-class virulence plasmid.
Wolf-Watz, Hans, Edgren, Tomas, Wang, He, Erttmann, Saskia, Fahlgren, Anna, Nuss, Aaron M, Fallman, Maria, Wang, He,, Avican, Kemal, Petra, Dersch, Dersch, Petra, Erttmann, Saskia F, Fällman, Maria,, Fahlgren, Anna,, Edgren, Tomas,, Nuss, Aaron M., Avican, Kemal,, Wolf-Watz, Hans,, Erttmann, Saskia F.,   +18 more
core   +1 more source

Investigation on the Antibacterial and Anti‐T3SS Activity of Traditional Myanmar Medicinal Plants [PDF]

Evidence-Based Complementary and Alternative Medicine, 2018
Myanmar has a rich pool of, but less known, medicinal plants with traditional knowledge. In this study, we aimed to investigate the inhibitory activity of traditional Myanmar medicinal plants against the type III secretion system (T3SS) of Salmonella enterica serovar Typhimurium UK‐1 χ8956 and the intestinal disease‐caused by microbes including S ...
Tianhong Li, Dongdong Zhang, Thaung Naing Oo, Myint Myint San, Aye Mya Mon, Pyae Phyo Hein, Yuehu Wang, Chunhua Lu, Xuefei Yang   +8 more
openaire   +2 more sources

A Phosphorylation Switch on Lon Protease Regulates Bacterial Type III Secretion System in Host

mBio, 2018
Most pathogenic bacteria deliver virulence factors into host cytosol through type III secretion systems (T3SS) to perturb host immune responses. The expression of T3SS is often repressed in rich medium but is specifically induced in the host environment.
Xiaofeng Zhou, Doron Teper, Maxuel O. Andrade, Tong Zhang, Sixue Chen, Wen-Yuan Song, Nian Wang   +6 more
doaj   +1 more source

Functional characterization of the type III secretion ATPase SsaN encoded by Salmonella pathogenicity island 2. [PDF]

PLoS ONE, 2014
A type III secretion system (T3SS) is utilized by a large number of gram-negative bacteria to deliver effectors directly into the cytosol of eukaryotic host cells.
Yukie Yoshida, Tsuyoshi Miki, Sayaka Ono, Takeshi Haneda, Masahiro Ito, Nobuhiko Okada   +5 more
doaj   +1 more source

Intrinsic Disorder as a New Frontier in Antimicrobial Resistance and Bacterial Fitness

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
The works examines the link between intrinsic disorder in bacterial protein structure, and bacterial function, and antimicrobial resistance. It highlights how flexible, disordered proteins support secretion, stress responses, desiccation protection, and virulence, while also suggesting that these adaptable regions may provide novel targets for ...
Jack O' Callaghan, Michael P. Ryan, Sarah Hudson, Damien Thompson   +3 more
wiley   +1 more source

Pseudomonas aeruginosa uses T3SS to inhibit diabetic wound healing [PDF]

Wound Repair and Regeneration, 2015
ABSTRACTDiabetic foot ulcers are responsible for more hospitalizations than any other complication of diabetes. Bacterial infection is recognized as an important factor associated with impaired healing in diabetic ulcers. Pseudomonas aeruginosa is the most frequently detected Gram‐negative pathogen in diabetic ulcers. P.
Josef, Goldufsky, Stephen J, Wood, Vijayakumar, Jayaraman, Omar, Majdobeh, Lin, Chen, Shanshan, Qin, Chunxiang, Zhang, Luisa A, DiPietro, Sasha H, Shafikhani   +8 more
openaire   +2 more sources