Results 81 to 90 of about 17,578 (215)
Proposed model for T3SS-dependent protein translocation by a binary AB toxin like mechanism.
T3SS translocators (t) and effectors (e) are secreted by the T3SS across the bacterial envelope (IM and OM) to the surface of the cell before host cell contact (1). Target cell sensing results in release of the surface localized T3SS substrates (2).
Roland Rosqvist (323456) +3 more
core +1 more source
Cross-talk between the Aeromonas hydrophila type III secretion system and lateral flagella system.
Aeromonas hydrophila is responsible for aeromonad septicaemia in fish, and gastroenteritis and wound infections in humans. The type III secretion system (T3SS) is utilized by aeromonads to inject protein effectors directly into host cells.
Yuhang Zhao, Jonathan Shaw
doaj +1 more source
Insights Into the Role of Lysine Acetylation of Non‐Histone Proteins in Plant Immunity
ABSTRACT Plant immunity is regulated by numerous transcriptional and posttranslational mechanisms. Among these, lysine acetylation, which is controlled by lysine acetyltransferases (KATs) and lysine deacetylases (KDACs), has been extensively studied, particularly in the context of epigenetic regulation through histone acetylation.
Jérémy Villette +5 more
wiley +1 more source
(A) Percentage of IM among total gated cells in cecal tissues from C57BL/6J mice (n = 3 per group) treated with Sm prior to inoculation with PBS (uninfected; UI) or wild-type (WT) STm, or invA (T3SS-1), ssaD (T3SS-2), or invA ssaD (T3SS-1 T3SS-2) mutant ...
Jesse Leeds (6954830) +6 more
core +1 more source
Generation and Characterization of a scFv Antibody Against T3SS Needle of Vibrio parahaemolyticus [PDF]
Vibrio parahaemolyticus, a halophilic gram-negative bacterium, is a food-borne pathogen that largely inhabits marine and estuarine environments, and poses a serious threat to human and animal health all over the world. The hollow "needle" channel, a specific assemble of T3SS which exists in most of gram-negative bacteria, plays a key role in the ...
Rongzhi, Wang +5 more
openaire +2 more sources
SUMMARY Bacterial wilt caused by Ralstonia solanacearum is a devastating disease that affects a wide range of crops, including tobacco. The pathogen promotes infection by secreting type III effector (T3E) proteins into host plants to facilitate pathogenicity; however, the molecular mechanisms for many of these effectors remain elusive.
Bo Nian +11 more
wiley +1 more source
The Yersinia enterocolitica type 3 secretion system (T3SS) as toolbox for studying the cell biological effects of bacterial Rho GTPase modulating T3SS effector proteins [PDF]
The bacterial effector proteins IpgB(1) and IpgB(2) of Shigella and Map of Escherichia coli activate the Rho GTPases Rac1, RhoA and Cdc42, respectively, whereas YopE and YopT of Yersinia inhibit these Rho family GTPases. We established a Yersinia toolbox which allows to study the cellular effects of these effectors in different combinations in the ...
Stefan, Wölke +2 more
openaire +2 more sources
Abstract Plant pathogenic bacteria cause massive losses in agriculture and damage to natural plant habitats. Bacterial pathogens not only reduce crop production, but they also reduce crop quality by releasing toxins into the environment. Pathogenic bacteria that invade plant tissues must overcome the plant's defense mechanisms. Plants possess an innate
Muluken Getahun, Zelalem Bekeko
wiley +1 more source
Proposed scenario for the evolution of NF-T3SS.
We propose that genes common to the flagellum and the NF-T3SS were present in the flagellar ancestor of NF-T3SS. They are designated as “T3SS genes”. Then we detail the evolution of this system to the extant NF-T3SSs.
Eduardo P. C. Rocha (7388) +1 more
core +1 more source
Structural and Functional Characterization of the Type Three Secretion System (T3SS) Needle of Pseudomonas aeruginosa [PDF]
International audienceThe type three secretion system (T3SS) is a macromolecular protein nano-syringe used by different bacterial pathogens to inject effectors into host cells. The extracellular part of the syringe is a needle-like filament formed by the
Pellequer, Jean-Luc +47 more
core +1 more source

