Results 191 to 200 of about 8,552 (215)

T6SS Mediated Stress Responses for Bacterial Environmental Survival and Host Adaptation [PDF]

International Journal of Molecular Sciences, 2021
The bacterial type VI secretion system (T6SS) is a protein secretion apparatus widely distributed in Gram-negative bacterial species. Many bacterial pathogens employ T6SS to compete with the host and to coordinate the invasion process. The T6SS apparatus consists of a membrane complex and an inner tail tube-like structure that is surrounded by a ...
Kai-Wei Yu, Liang Yang, Yang Fu
exaly   +3 more sources

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T6SS: shoot and scrub

Nature Reviews Microbiology, 2020
This study shows that T6SS-mediated killing of competitors is most effective if a lytic toxin is injected.
openaire   +2 more sources

A duet of T6SS effectors

Cell Host & Microbe
How do gut bacteria outcompete rivals in dense microbial ecosystems? In this issue of Cell Host & Microbe, Li et al.1 report a Bacteroides T6SS adaptor protein C-orchestrated co-secretion mechanism of T6SS effectors Bacteroides T6SS phosphatase effector A and Bacteroides T6SS amidase effector B in gut Bacteroidota, thereby revealing a conserved ...
Lingfang, Zhu, Xihui, Shen
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A new class of polymorphic T6SS effectors and tethers

2022
Abstract Bacteria use the type VI secretion system (T6SS) to deliver toxic effectors into bacterial or eukaryotic cells during interbacterial competition, host colonization, or when resisting predation. The identity of many effectors remains unknown.
Katarzyna Kanarek, Chaya Mushka Fridman, Eran Bosis, Dor Salomon   +3 more
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Refined egoist: The toxin–antitoxin immune system of T6SS

Microbial Pathogenesis
The Type VI secretory system (T6SS) is a key regulatory network in the bacterial system, which plays an important role in host-pathogen interactions and maintains cell homeostasis by regulating the release of effector proteins in specific competition.
Ziduo, Chen, Yikai, Mao, Yinzhou, Song, Mengxuan, Dou, Ke, Shang, Zuhua, Yu, Ke, Ding, Songbiao, Chen   +7 more
openaire   +2 more sources

Klebsiella pneumoniae T6SS impact in IBDs

Journal of Crohn's and Colitis
Abstract Background and aims Our hypothesis is that Klebsiella pneumoniae (Kp) Type VI Secretion System (T6SS), normally used for bacteria competition during host colonization have a collateral impact on the host inflammatory pathway (Fig1).
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Balanced role of T3SS and T6SS in contribution to the full virulence of Edwardsiella piscicida

Fish & Shellfish Immunology, 2019
Edwardsiella piscicida is an important pathogen that infects a wide range of hosts, from fish to human. Its infection leads to extensive losses in a diverse array of commercially important fish, like Japanese flounder, turbot, and tilapia. During the infection, type III secretion system (T3SS) and type VI secretion system (T6SS) of E.
Tianjian Hu, Ran Chen, Lingzhi Zhang, Zhuang Wang, Dahai Yang, Yuanxing Zhang, Xiaohong Liu, Qin Liu   +7 more
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Distribution of type VI secretion system (T6SS) in clinical Klebsiella pneumoniae strains from a Chinese hospital and its potential relationship with virulence and drug resistance

Microbial Pathogenesis, 2022
Wenjian Liao, Haihua Huang, Qi-Sen Huang   +2 more
exaly  

Killing of Gram-negative and Gram-positive bacteria by a bifunctional cell wall-targeting T6SS effector

Proceedings of the National Academy of Sciences of the United States of America, 2021
Felipe Cava, Nguyen-Hung Le, Juvenal Lopez   +2 more
exaly  

Killing in the name of: T6SS structure and effector diversity

Microbiology (United Kingdom), 2023
Luke P Allsopp, Patricia Bernal
exaly