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T6SS-effector hunters uncover PIX: a novel delivery/marker domain

Trends in Microbiology
Gram-negative bacteria use the T6SS to eject effectors into prey cells, aided by delivery domains. Recently uncovered by Carobbi et al., a new delivery domain, PIX, allowed the identification of hundreds of new effectors. They are order- and function-specific and exclusively orphan effectors, raising novel questions in the field.
openaire   +2 more sources

Killing in the Name Of: T6SS Structure and Effector Diversity

Microbiology (United Kingdom), 2023
Luke P Allsopp, Patricia Bernal
exaly  

Endogenous Membrane Stress Induces T6SS Activity in Pseudomonas aeruginosa

Proceedings of the National Academy of Sciences of the United States of America, 2021
Anne-Sophie Stolle   +2 more
exaly  

The Two-Component System FleS/FleR Represses H1-T6SS via Cyclic Di-GMP Signaling in Pseudomonas aeruginosa.

Applied and Environmental Microbiology, 2022
Tian Zhou, Lian-Hui Zhang, Zeling Xu
exaly  

Identification of T6SS-Dependent Effector and Immunity Proteins by Tn-Seq in Vibrio cholerae

Proceedings of the National Academy of Sciences of the United States of America, 2013
Deborah R Yoder-Himes   +2 more
exaly  

A Family of T6SS Antibacterial Effectors Related to l,d-Transpeptidases Targets the Peptidoglycan

Cell Reports, 2020
Ankur V Patel   +2 more
exaly  

The Pseudomonas aeruginosa T6SS-VgrG1b Spike Is Topped by a PAAR Protein Eliciting DNA Damage to Bacterial Competitors

Proceedings of the National Academy of Sciences of the United States of America, 2018
Luke P Allsopp   +2 more
exaly  

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