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T6SS-effector hunters uncover PIX: a novel delivery/marker domain
Trends in MicrobiologyGram-negative bacteria use the T6SS to eject effectors into prey cells, aided by delivery domains. Recently uncovered by Carobbi et al., a new delivery domain, PIX, allowed the identification of hundreds of new effectors. They are order- and function-specific and exclusively orphan effectors, raising novel questions in the field.
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Killing in the Name Of: T6SS Structure and Effector Diversity
Microbiology (United Kingdom), 2023Luke P Allsopp, Patricia Bernal
exaly
Endogenous Membrane Stress Induces T6SS Activity in Pseudomonas aeruginosa
Proceedings of the National Academy of Sciences of the United States of America, 2021Anne-Sophie Stolle +2 more
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Identification of T6SS-Dependent Effector and Immunity Proteins by Tn-Seq in Vibrio cholerae
Proceedings of the National Academy of Sciences of the United States of America, 2013Deborah R Yoder-Himes +2 more
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A Family of T6SS Antibacterial Effectors Related to l,d-Transpeptidases Targets the Peptidoglycan
Cell Reports, 2020Ankur V Patel +2 more
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Proceedings of the National Academy of Sciences of the United States of America, 2018
Luke P Allsopp +2 more
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Luke P Allsopp +2 more
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