Results 31 to 40 of about 9,692 (159)
A subcellular biochemical model for T6SS dynamics reveals winning competitive strategies [PDF]
PNAS Nexus, 2021 AbstractThe Type VI secretion system (T6SS) is a broadly distributed interbacterial weapon that can be used to eliminate competing bacterial populations. Although unarmed target populations are typically used to study T6SS function, bacteria most likely encounter other T6SS-armed competitors in nature. The outcome of such battles is not well understood,
Yuexia Luna Lin +4 more
openaire +4 more sources
Molecular processes underlying synergistic linuron mineralization in a triple-species bacterial consortium biofilm revealed by differential transcriptomics [PDF]
, 2018 The proteobacteria Variovorax sp. WDL1, Comamonas testosteroni WDL7, and Hyphomicrobium sulfonivorans WDL6 compose a triple-species consortium that synergistically degrades and grows on the phenylurea herbicide linuron.
Anders +52 more
core +2 more sources
T6SS: The bacterial “Fight Club” in the host gut
PLOS Pathogens, 2017 The mammalian gut is home to a densely populated community of microorganisms that not only provide their host with nutritional benefits but also offer protection against foreign pathogens. Since the gut is an environment limited in both space and nutrients, these microbes have evolved multiple mechanisms and strategies to either coexist or compete with
Thibault G. Sana +2 more
openaire +4 more sources
Differential Role of the T6SS in Acinetobacter baumannii Virulence
PLOS ONE, 2015 Las bacterias gramnegativas, como Acinetobacter baumannii, son una carga cada vez mayor en los hospitales de todo el mundo con una propagación alarmante de cepas multirresistentes (MDR). Aquí, comparamos una cepa tipo (ATCC17978), un aislado no clínico (DSM30011) y cepas MDR de A.
Guillermo D. Repizo +8 more
openaire +5 more sources
Structural analysis of Pseudomonas aeruginosa H3‐T6SS immunity proteins [PDF]
FEBS Letters, 2016 The Pseudomonas aeruginosa PldB protein is a transkingdom effector secreted by the Type VI Secretion System (T6SS). PA5088, PA5087, and PA5086 are three immunity proteins that can suppress the virulence of PldB. We report the crystal structures of PA5088 and PA5087 at 2.0 and 2.1 Å resolution, respectively.
Xiao-Yun, Yang +6 more
openaire +2 more sources
Calcium Promotes T6SS-Mediated Killing and Aggregation between Competing Symbionts
Microbiology Spectrum, 2022 Microbes deploy competitive mechanisms to gain access to resources such as nutrients or space within an ecological niche. Identifying when and where these strategies are employed can be challenging given the complexity and variability of most natural systems; therefore, studies evaluating specific cues that conditionally regulate interbacterial ...
Lauren Speare +2 more
openaire +3 more sources
A Vibrio T6SS-Mediated Lethality in an Aquatic Animal Model
Microbiology Spectrum, 2023 The rise in sea surface temperature has been linked to the spread of bacteria belonging to the genus Vibrio and the human illnesses associated with them. Since vibrios often share virulence traits horizontally, a better understanding of their virulence potential and determinants can prepare ...
Hadar Cohen +3 more
openaire +3 more sources
Molecular weaponry:diverse effectors delivered by the Type VI secretion system [PDF]
, 2015 The Type VI secretion system is a widespread bacterial nanomachine, used to deliver toxins directly into eukaryotic or prokaryotic target cells. These secreted toxins, or effectors, act on diverse cellular targets, and their action provides the attacking
Alcoforado Diniz, Juliana +2 more
core +2 more sources
Atomic Structure of T6SS Reveals Interlaced Array Essential to Function [PDF]
Cell, 2015 Type VI secretion systems (T6SSs) are newly identified contractile nanomachines that translocate effector proteins across bacterial membranes. The Francisella pathogenicity island, required for bacterial phagosome escape, intracellular replication, and virulence, was presumed to encode a T6SS-like apparatus. Here, we experimentally confirm the identity
Clemens, Daniel L +4 more
openaire +5 more sources
The Vibrio Cholerae Type VI Secretion System: Evaluating its Role in the Human Disease Cholera [PDF]
, 2010 Vibrio cholerae, the marine bacterium responsible for the diarrheal disease cholera, utilizes a multitude of virulence factors to cause disease. The importance of two of these factors, the toxin co-regulated pilus (TCP) and cholera toxin (CT), has been ...
Sarah T. Miyata +5 more
core +1 more source