Results 41 to 50 of about 8,552 (215)

Polar localization of the ATPase ClpV-5 occurs independent of type VI secretion system apparatus proteins in Burkholderia thailandensis

BMC Research Notes, 2019
Objective ClpV, the ATPase of the type VI secretion system (T6SS) recycles cytoplasmic T6SS proteins following effector translocation. Fluorescent protein fusions to ClpV showed that it localizes to discrete and dynamic foci.
Jan Lennings, Christian Mayer, Munira Makhlouf, Heike Brötz-Oesterhelt, Sandra Schwarz   +4 more
doaj   +1 more source

Bioinformatic Analysis of the Campylobacter jejuni Type VI Secretion System and Effector Prediction

Frontiers in Microbiology, 2021
The Type VI Secretion System (T6SS) has important roles relating to bacterial antagonism, subversion of host cells, and niche colonisation. Campylobacter jejuni is one of the leading bacterial causes of human gastroenteritis worldwide and is a commensal ...
Luca Robinson, Janie Liaw, Zahra Omole, Dong Xia, Arnoud H. M. van Vliet, Nicolae Corcionivoschi, Nicolae Corcionivoschi, Abderrahman Hachani, Ozan Gundogdu   +8 more
doaj   +1 more source

Diversity and distribution of Type VI Secretion System gene clusters in bacterial plasmids

Scientific Reports, 2022
Type VI Secretion System (T6SS) is a nanomolecular apparatus that allows the delivery of effector molecules through the cell envelope of a donor bacterium to prokaryotic and/or eukaryotic cells, playing a role in the bacterial competition, virulence, and
Sergio Morgado, Ana Carolina Vicente
doaj   +1 more source

Bile Salts Modulate the Mucin-Activated Type VI Secretion System of Pandemic Vibrio cholerae. [PDF]

PLoS Neglected Tropical Diseases, 2015
The causative agent of cholera, Vibrio cholerae, regulates its diverse virulence factors to thrive in the human small intestine and environmental reservoirs.
Verena Bachmann, Benjamin Kostiuk, Daniel Unterweger, Laura Diaz-Satizabal, Stephen Ogg, Stefan Pukatzki   +5 more
doaj   +1 more source

Role of the type VI secretion systems during disease interactions of Erwinia amylovora with its plant host

BMC Genomics, 2017
Background Type VI secretion systems (T6SS) are widespread among Gram-negative bacteria and have a potential role as essential virulence factors or to maintain symbiotic interactions. Three T6SS gene clusters were identified in the genome of E. amylovora
Tim Kamber, Joël F. Pothier, Cosima Pelludat, Fabio Rezzonico, Brion Duffy, Theo H. M. Smits   +5 more
doaj   +1 more source

A proposed model of H2-T6SS-mediated Cu²⁺ transport in P. aeruginosa.

, 2019
Under Cu2+ rich conditions, the copper homeostasis regulator CueR represses the expression of H2-T6SS genes. The Cu2+ transport is mainly dependent on the known systems, such as CopY, CueA and CusR/S.
Tietao Wang (637621), Linghui Xu (6295400), Yuying Han (8067419), Qiong Liu (299371), Gukui Chen (6706658), Min Wu (41570), Haihua Liang (1993753), Qinqin Pu (2831669), Yani Zhang (446928)   +8 more
core   +1 more source

Data_Sheet_1_Delivery of the Pseudomonas aeruginosa Phospholipase Effectors PldA and PldB in a VgrG- and H2-T6SS-Dependent Manner.PDF

, 2019
The bacterial pathogen Pseudomonas aeruginosa uses three type VI secretion systems (T6SSs) to drive a multitude of effector proteins into eukaryotic or prokaryotic target cells.
Sarah Wettstadt (7107035), Thomas E. Wood (2739400), Selina Fecht (7107038), Alain Filloux (190708)   +3 more
core   +1 more source

Virulence Genotype and Correlation of Clinical Severeness with Presence of the Type VI Secretion System in Klebsiella pneumoniae Isolates Causing Bloodstream Infections

Infection and Drug Resistance, 2022
Yin Zhang, Yuanhong Xu, Ying Huang Department of Clinical Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei, People’s Republic of ChinaCorrespondence: Ying Huang; Yuanhong Xu, Department of Clinical Laboratory, The First ...
Zhang Y, Xu Y, Huang Y
doaj  

Identification and Characterization of an Antibacterial Type VI Secretion System in the Carbapenem-Resistant Strain Klebsiella pneumoniae HS11286

Frontiers in Cellular and Infection Microbiology, 2017
The type VI secretion system (T6SS) is a class of sophisticated cell contact-dependent apparatus with anti-eukaryotic or anti-bacterial function. Klebsiella pneumoniae is one of the most common bacterial pathogens with resistance to the carbapenem ...
Lu Liu, Meiping Ye, Xiaobin Li, Jun Li, Zixin Deng, Yu-Feng Yao, Hong-Yu Ou   +6 more
doaj   +1 more source

Pathogenicity and virulence regulation of Vibrio cholerae at the interface of host-gut microbiome interactions

Virulence, 2020
The Gram-negative bacterium Vibrio cholerae is responsible for the severe diarrheal pandemic disease cholera, representing a major global public health concern.
Ansel Hsiao, Jun Zhu
doaj   +1 more source