Results 41 to 50 of about 8,918 (214)

Composition, function, and regulation of T6SS in Pseudomonas aeruginosa

Microbiological Research, 2015
Bacterial cells can communicate with their surrounding environment through secretion systems. Type VI secretion system (T6SS) is one of the most recently discovered secretion systems, which is distributed widely in Gram-negative bacteria such as Pseudomonas aeruginosa (P. aeruginosa), an important opportunistic pathogen.
Chen, Lihua, Zou, Yaru, She, Pengfei, Wu, Yong   +3 more
openaire   +2 more sources

Transfer of T6SSSPI-19 from Salmonella Gallinarum to Salmonella Typhimurium Lacking T6SSSPI-6 Complements its Colonization Defect in Mice

Polish Journal of Microbiology, 2023
Salmonella genus harbors five Type VI Secretion System (T6SS) gene clusters. The T6SS encoded in SPI-6 (T6SSSPI-6) contributes to Salmonella Typhimurium colonization of chickens and mice, while the T6SS encoded in SPI-19 (T6SSSPI-19) of Salmonella ...
Pezoa David, Blondel Carlos J., Amaya Fernando A., Santiviago Carlos A.   +3 more
doaj   +1 more source

Bioinformatic Analysis of the Campylobacter jejuni Type VI Secretion System and Effector Prediction

Frontiers in Microbiology, 2021
The Type VI Secretion System (T6SS) has important roles relating to bacterial antagonism, subversion of host cells, and niche colonisation. Campylobacter jejuni is one of the leading bacterial causes of human gastroenteritis worldwide and is a commensal ...
Luca Robinson, Janie Liaw, Zahra Omole, Dong Xia, Arnoud H. M. van Vliet, Nicolae Corcionivoschi, Nicolae Corcionivoschi, Abderrahman Hachani, Ozan Gundogdu   +8 more
doaj   +1 more source

Endogenous membrane stress induces T6SS activity in Pseudomonas aeruginosa [PDF]

Proceedings of the National Academy of Sciences, 2020
Significance In this study, we applied a CRISPR interference approach to knock down expression of essential genes involved in cell envelope biogenesis and determined if this can trigger Pseudomonas aeruginosa T6SS apparatus assembly.
Anne-Sophie Stolle, Bradley Thomas Meader, Jonida Toska, John J. Mekalanos   +3 more
openaire   +2 more sources

Polar localization of the ATPase ClpV-5 occurs independent of type VI secretion system apparatus proteins in Burkholderia thailandensis

BMC Research Notes, 2019
Objective ClpV, the ATPase of the type VI secretion system (T6SS) recycles cytoplasmic T6SS proteins following effector translocation. Fluorescent protein fusions to ClpV showed that it localizes to discrete and dynamic foci.
Jan Lennings, Christian Mayer, Munira Makhlouf, Heike Brötz-Oesterhelt, Sandra Schwarz   +4 more
doaj   +1 more source

A proposed model of H2-T6SS-mediated Cu²⁺ transport in P. aeruginosa.

, 2019
Under Cu2+ rich conditions, the copper homeostasis regulator CueR represses the expression of H2-T6SS genes. The Cu2+ transport is mainly dependent on the known systems, such as CopY, CueA and CusR/S.
Tietao Wang (637621), Linghui Xu (6295400), Yuying Han (8067419), Qiong Liu (299371), Gukui Chen (6706658), Min Wu (41570), Haihua Liang (1993753), Qinqin Pu (2831669), Yani Zhang (446928)   +8 more
core   +1 more source

Genetically complemented V. coralliilyticus T6SS mutant challenge assay.

, 2020
The V. coralliilyticus OCN008 ΔvasK strain (T6SS-) and the ΔvasK strain carrying a plasmid expressing a wild-type copy of vasK (pBU270) were challenged against T6SS+ V. cholerae (black bars) or T6SS+ V. cholerae (grey bars). V. cholerae strains were also
Farooq Azam (41635), Ryan Guillemette (8367684), Mihika Jalan (8367687), Claudia C. Häse (7420727), Blake Ushijima (131681)   +4 more
core   +1 more source

Role of the type VI secretion systems during disease interactions of Erwinia amylovora with its plant host

BMC Genomics, 2017
Background Type VI secretion systems (T6SS) are widespread among Gram-negative bacteria and have a potential role as essential virulence factors or to maintain symbiotic interactions. Three T6SS gene clusters were identified in the genome of E. amylovora
Tim Kamber, Joël F. Pothier, Cosima Pelludat, Fabio Rezzonico, Brion Duffy, Theo H. M. Smits   +5 more
doaj   +1 more source

Diversity and distribution of Type VI Secretion System gene clusters in bacterial plasmids

Scientific Reports, 2022
Type VI Secretion System (T6SS) is a nanomolecular apparatus that allows the delivery of effector molecules through the cell envelope of a donor bacterium to prokaryotic and/or eukaryotic cells, playing a role in the bacterial competition, virulence, and
Sergio Morgado, Ana Carolina Vicente
doaj   +1 more source

Pathogenicity and virulence regulation of Vibrio cholerae at the interface of host-gut microbiome interactions

Virulence, 2020
The Gram-negative bacterium Vibrio cholerae is responsible for the severe diarrheal pandemic disease cholera, representing a major global public health concern.
Ansel Hsiao, Jun Zhu
doaj   +1 more source