Results 31 to 40 of about 8,552 (215)
Acid-induced type VI secretion system is regulated by ExoR-ChvG/ChvI signaling cascade in Agrobacterium tumefaciens. [PDF]
PLoS Pathogens, 2012 The type VI secretion system (T6SS) is a widespread, versatile protein secretion system in pathogenic Proteobacteria. Several T6SSs are tightly regulated by various regulatory systems at multiple levels.
Chih-Feng Wu +3 more
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The Biological and Regulatory Role of Type VI Secretion System of Klebsiella pneumoniae
Infection and Drug Resistance, 2023 Wenke Liu,1,* Min Li,1,* Shiwen Cao,1 Hafiz Muhammad Ishaq,2 Huajie Zhao,1 Fan Yang,1 Liang Liu1 1Department of Pathogenic Biology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, People’s Republic of China; 2Faculty of ...
Liu W +6 more
doaj
A modular effector with a DNase domain and a marker for T6SS substrates [PDF]
Nature Communications, 2019 AbstractBacteria deliver toxic effectors via type VI secretion systems (T6SSs) to dominate competitors, but the identity and function of many effectors remain unknown. Here we identify a Vibrio antibacterial T6SS effector that contains a previously undescribed, widespread DNase toxin domain that we call PoNe (Polymorphic Nuclease effector).
Biswanath Jana +3 more
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Type VI secretion system : secretion by a contractile nanomachine [PDF]
, 2015 The type VI secretion systems (T6SS) are present in about a quarter of all Gram-negative bacteria. Several key components of T6SS are evolutionarily related to components of contractile nanomachines such as phages and R-type pyocins. The T6SS assembly is
Basler, Marek
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T6SS: The bacterial “Fight Club” in the host gut
PLOS Pathogens, 2017 The mammalian gut is home to a densely populated community of microorganisms that not only provide their host with nutritional benefits but also offer protection against foreign pathogens. Since the gut is an environment limited in both space and nutrients, these microbes have evolved multiple mechanisms and strategies to either coexist or compete with
Thibault G. Sana +2 more
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NrtR Mediated Regulation of H1-T6SS in Pseudomonas aeruginosa
Microbiology Spectrum, 2022 NrtR is a Nudix-related transcriptional regulator and controls the NAD cofactor biosynthesis in bacteria. P. aeruginosa NrtR binds to the intergenic region between nadD2 and pncA to repress the expression of the two operons, therefore controlling the NAD biosynthesis ...
Xinxin Zhang +9 more
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baumannii T6SS gene cluster: Systematic review of genes important for the T6SS activity.
, 2023 The A. (A) Schematic model of A. baumannii T6SS nanomachine and representation of the genetic organization of a vgrG locus and the T6SS cluster from A. baumannii 17978. The T6SS gene cluster of A.
Eric Durand (197728) +11 more
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Composition, function, and regulation of T6SS in Pseudomonas aeruginosa
Microbiological Research, 2015 Bacterial cells can communicate with their surrounding environment through secretion systems. Type VI secretion system (T6SS) is one of the most recently discovered secretion systems, which is distributed widely in Gram-negative bacteria such as Pseudomonas aeruginosa (P. aeruginosa), an important opportunistic pathogen.
Chen, Lihua +3 more
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Endogenous membrane stress induces T6SS activity in Pseudomonas aeruginosa [PDF]
Proceedings of the National Academy of Sciences, 2020 Significance In this study, we applied a CRISPR interference approach to knock down expression of essential genes involved in cell envelope biogenesis and determined if this can trigger Pseudomonas aeruginosa T6SS apparatus assembly.
Anne-Sophie Stolle +3 more
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Polish Journal of Microbiology, 2023 Salmonella genus harbors five Type VI Secretion System (T6SS) gene clusters. The T6SS encoded in SPI-6 (T6SSSPI-6) contributes to Salmonella Typhimurium colonization of chickens and mice, while the T6SS encoded in SPI-19 (T6SSSPI-19) of Salmonella ...
Pezoa David +3 more
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