T6SS: killing two bugs with one stone [PDF]
Trends in Microbiology, 2021 International audienceBacteria deploy the type VI secretion system (T6SS) to inject effectors into bacterial rivals. Contrary to the prevailing model, a recent study expands the target range of the T6SS by demonstrating that it delivers and potentializes
Cascales, E. +2 more
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Metabolic disharmony and sibling conflict mediated by T6SS [PDF]
Microbial Cell, 2018 Bacteria in nature live in taxonomically complex communities where multitude of species and strains inhabit the same niches and compete for limited resources and space.
Daniel Wall, Vera Troselj
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Killing in the name of: T6SS structure and effectors diversity
Microbiology, 2023 The life of bacteria is challenging, to endure bacteria employ a range of mechanisms to optimise their environment, including deploying the type VI secretion system (T6SS).
Allsopp, Luke +5 more
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The Pseudomonas putida T6SS is a plant warden against phytopathogens [PDF]
The ISME Journal, 2016 Bacterial type VI secretion systems (T6SSs) are molecular weapons designed to deliver toxic effectors into prey cells. These nanomachines play an important role in inter-bacterial competition and provide advantages to T6SS active strains in polymicrobial
Allsopp, LP +3 more
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A visual assay to monitor T6SS-mediated bacterial competition [PDF]
Journal of Visualized Experiments, 2013 Type VI secretion systems (T6SSs) are molecular nanomachines allowing Gram-negative bacteria to transport and inject proteins into a wide variety of target cells1,2. The T6SS is composed of 13 core components and displays structural similarities with the
Lossi, Nadine S +5 more
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Differential Role of the T6SS in Acinetobacter baumannii Virulence [PDF]
PLOS ONE, 2015 Gram-negative bacteria, such as Acinetobacter baumannii, are an increasing burden in hospitals worldwide with an alarming spread of multi-drug resistant (MDR) strains.
Marie-Laure Foucault-Grunenwald (393002) +41 more
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Pseudomonas aeruginosa type six secretion system (T6SS): The Tse7 DNase effector and post-translational regulation of the H1-T6SS [PDF]
, 2018 Pseudomonas aeruginosa is a versatile opportunistic bacterial pathogen. Its ability to successfully colonize various environments and hosts is partly due to the capability of P. aeruginosa to outcompete other bacteria.
Pissaridou, Panayiota
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T6SS Accessory Proteins, Including DUF2169 Domain-Containing Protein and Pentapeptide Repeats Protein, Contribute to Bacterial Virulence in T6SS Group_5 of Burkholderia glumae BGR1 [PDF]
Plants, 2021 Burkholderia glumae are bacteria pathogenic to rice plants that cause a disease called bacterial panicle blight (BPB) in rice panicles. BPB, induced by B. glumae, causes enormous economic losses to the rice agricultural industry. B.
Namgyu Kim +5 more
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Atomic Structure of T6SS Reveals Interlaced Array Essential to Function [PDF]
Cell, 2015 SummaryType VI secretion systems (T6SSs) are newly identified contractile nanomachines that translocate effector proteins across bacterial membranes. The Francisella pathogenicity island, required for bacterial phagosome escape, intracellular replication,
Horwitz, Marcus A. +7 more
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Proteogenomic annotation of T6SS components identified in Bacteroides fragilis secretome [PDF]
Frontiers in MicrobiologyIntroductionBacteroides fragilis (Bf)’s T6SS locus has been characterized and shown to have functional activity in competition experiments. It has been demonstrated that symbiont nontoxigenic Bf strains have a more effective “weapon” effect on pathogenic
Anna A. Vanyushkina +14 more
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