Results 181 to 190 of about 30,445,587 (352)

Angiocentric T-cell lymphoma in a cat. [PDF]

J Vet Diagn Invest
Krebs KH, Strandberg NJ, Carvallo-Chaigneau FR, Freeman MD.   +3 more
europepmc   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

T cell-intrinsic VISTA expression promotes resistance to CTLA-4 blockade by restricting CD8+ T cell responses. [PDF]

J Clin Invest
Gilmour C, DeLaney E, Parthasarathy PB, Roy D, Ta HM, Zakeri A, Elguera Grandez P, Patnaik S, Zhang K, Juric I, Rangan R, Al-Hilli Z, Tufaro A, Min B, Weinberg SE, Chan TA, Silver NL, Avril S, Alban T, Wang LL.   +19 more
europepmc   +1 more source

Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma.

Cell, 2019
Moshe Sade-Feldman, K. Yizhak, Stacey L. Bjorgaard, John P. Ray, Carl G. de Boer, R. Jenkins, David J. Lieb, Jonathan H. Chen, Dennie T. Frederick, Michal Barzily-Rokni, S. Freeman, A. Reuben, P. Hoover, A. Villani, E. Ivanova, A. Portell, P. Lizotte, A. Aref, J. Eliane, Marc R. Hammond, Hans Vitzthum, S. Blackmon, Bo Li, V. Gopalakrishnan, S. Reddy, Z. Cooper, C. Paweletz, D. Barbie, A. Stemmer-Rachamimov, K. Flaherty, J. Wargo, G. Boland, R. Sullivan, G. Getz, N. Hacohen   +34 more
semanticscholar   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Cardiotoxicity of T cell immunotherapies. [PDF]

Nat Rev Cardiol
Raddatz MA, Stein-Merlob AF, Mahmood SS, Ganatra S, Addison D, Lin TL, Larson SM, Yang EH.   +7 more
europepmc   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Single-Cell Transcriptome Reveals the Heterogeneity of T Cells in Mice with Systemic Lupus Erythematosus and Neuronal Inflammation

Journal of Inflammation Research
Zhijie Shi, Haihong Qin, Hao Wu Fudan University, Shanghai, People’s Republic of ChinaCorrespondence: Haihong Qin; Hao Wu, Email tjqhh1982@163.com; seaseewh@163.comIntroduction: Systemic lupus erythematosus is a heterogeneous autoimmune disease.
Shi Z, Qin H, Wu H
doaj  

Dissection of the T cell infiltrate in mouse pancreatic tumors reveals an extensive and diverse tumor-reactive T cell repertoire. [PDF]

Sci Adv
Kehm H, Zens S, Baumann D, Meng Z, de Ru AH, Tjokrodirijo RTN, Vent C, Murawjew O, Braun S, Weiss A, Bieberich F, Konrad A, Lucato F, Kühner J, Minguez SG, Tan CL, Förster JD, Salek M, Riemer AB, Volkmar M, van Veelen P, Poschke I, Offringa R.   +22 more
europepmc   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source