Results 231 to 240 of about 4,664,465 (319)

Exhausted T cell phenotypes in disseminated coccidioidomycosis. [PDF]

JCI Insight
Whitehill GD, Stephens AV, Thauland TJ, Moreno Lastre MA, Tate MM, Beyhan S, Johnson RH, Thompson GR, Garcia-Lloret M, Butte MJ.   +9 more
europepmc   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Wnt Signaling Downregulation Mediates T Cell Apoptosis Following OKT3-Induced T Cell Activation in Preclinical Models. [PDF]

FASEB J
Choi M, Park D, Lee DH, Choi CH, Jo M, Jeong SY, Lim SY, Park D, Moon KS.   +8 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Checkpoint blockade and the stem-like T cell trade-off. [PDF]

Mol Oncol
Mazet JM, Joyce JA.
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Natural Killer T Cell Function in Lymphoma Patients. [PDF]

Biomolecules
Derakhshandeh R, Lee MS, Zhu Y, Asiedu EB, Reader J, Younis RH, Kimball AS, Glynn N, Kallen M, Webb TJ.   +9 more
europepmc   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Systemic pre-conditioning favors effector over exhausted CD8 T-cell subsets following Sup2-IL33 armored CAR T-cell therapy. [PDF]

J Immunother Cancer
Ferry SL, Abdullah L, Balasubramanian A, Nowak EC, Carl A, Turnquist A, Mohamed A, Usherwood E, Sundrud M, Huang Y.   +9 more
europepmc   +1 more source