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CAR T Cells

2020
In 1891, Dr. William B. Coley, an American surgeon, made a compelling observation that immune system can be triggered to shrink tumors. The quest to exploit the power of immunotherapy however was forestalled by an era of chemotherapy that ensued.
Ranjit, Nair, Jason, Westin
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T-cell therapies for T-cell lymphoma

Cytotherapy, 2019
T-cell lymphomas represent a subpopulation of non-Hodgkin lymphomas with poor outcomes when treated with conventional chemotherapy. A variety of novel agents have been introduced as new treatment strategies either as first-line treatment or in conjunction with chemotherapy. Immunotherapy has been demonstrated to be a promising area for new therapeutics,
Keri Toner   +2 more
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T Cell Receptors and T Cell Development

1996
Birds provide a valuable model system for the study of early development. Studies of immune system development and function in chickens have contributed to some of the central tenets in immunology. These include:(1) allorecognition by lymphocytes in graft-vs-host (GVH) reactions (Simonsen 1985), (2) clonal reactivity of immunocompetent lymphocytes ...
C H, Chen   +6 more
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Suppressor T Cells

The Journal of Immunology, 1972
Abstract The antigen-induced DNA synthetic response of a number of different thymocyte populations was studied in the spleens of lethally irradiated recipients by incorporation of 125I 5-iodo-2-deoxyuridine. The response of certain cell combinations was not only less than the sum of the two responding alone but less than one of the ...
Gershon, R K   +3 more
openaire   +2 more sources

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