Results 271 to 280 of about 4,664,465 (319)

Immune dysregulation in endometriosis: the T cell perspective. [PDF]

Front Immunol
Sisnett DJ, Zutautas KB, Vo DHN, Ravishanker K, Holmes JP, Wodz A, Tayade C.   +6 more
europepmc   +1 more source

Decoding the human CD4⁺ T cell epitope repertoire for Lassa fever virus reveals T cell-based pan-mammarenavirus vaccine candidates. [PDF]

Cell Rep Med
Lee Y, Siddiqui L, Tarke A, Kim M, Michaelis T, Macias M, Phillips E, Mallal S, Trevizani R, Frazier A, Scheuermann RH, Zuniga A, Zmasek C, Spurgers K, Akintunde G, Stonier SW, Gagliardi TB, Warfield K, Li H, Hastie KM, Saphire EO, Tan GS, Grifoni A, Sette A.   +23 more
europepmc   +1 more source

Enhancement of CD117-Targeted Bispecific T-cell Engagement by CD33-Targeted Bispecific T-cell Costimulation in Acute Myeloid Leukemia. [PDF]

Cancer Res Commun
Hofstetter M, Volta L, Koch C, Rey MG, Maurer M, Gönüllü N, Pellegrino C, Gobbi C, Schneiter F, Manfredi F, Magnani CF, Elsayed A, Schroeder T, Neri D, Manz MG.   +14 more
europepmc   +1 more source

Optimizing In Vivo CAR T-cell Engineering for Cancer Immunotherapy. [PDF]

Cancer Res
Wang R, Yu J, Caligiuri MA, Ma S.
europepmc   +1 more source

Aberrant IL-21/STAT3 signaling disrupts regulatory T cell function and CD4⁺ T cell homeostasis in children with type 1 diabetes. [PDF]

Front Immunol
Sun X, Zhao J, Liu J, Zhou W.
europepmc   +1 more source

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The T Cell Receptor

Science, 1987
The primary structure of T cell receptor proteins and genes is well understood. Immunologists are now trying to understand the properties of these interesting molecules. Evidence suggests that T cell αβ receptors recognize a complex of an antigen-derived peptide bound to one of the cell-surface products of the major histocompatibility complex (MHC ...
P, Marrack, J W, Kappler
openaire   +3 more sources

CAR T Cells

2020
In 1891, Dr. William B. Coley, an American surgeon, made a compelling observation that immune system can be triggered to shrink tumors. The quest to exploit the power of immunotherapy however was forestalled by an era of chemotherapy that ensued.
Ranjit, Nair, Jason, Westin
openaire   +3 more sources

T-cell therapies for T-cell lymphoma

Cytotherapy, 2019
T-cell lymphomas represent a subpopulation of non-Hodgkin lymphomas with poor outcomes when treated with conventional chemotherapy. A variety of novel agents have been introduced as new treatment strategies either as first-line treatment or in conjunction with chemotherapy. Immunotherapy has been demonstrated to be a promising area for new therapeutics,
Keri Toner, Catherine M. Bollard, Hema Dave   +2 more
openaire   +2 more sources