Results 111 to 120 of about 1,626,605 (265)

The TCXpress lane to T-cell receptor-engineered T cells. [PDF]

Blood Adv
Biernacki MA.
europepmc   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Correction to "Synthetic T-Cell Receptor-like Protein Behaves as a Janus Particle in Solution". [PDF]

J Am Chem Soc
Sakamoto-Rablah E, Bye J, Modak A, Hooker A, Uddin S, McManus JJ.   +5 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

T-cell receptor clonotypic diversity and specialization in digestive system cancers. [PDF]

NPJ Precis Oncol
Li L, Li J, Wang F, Jiang R, Wang H, Li X, Zhen Y.   +6 more
europepmc   +1 more source

The T cell antigen receptor [PDF]

Biochemical Journal, 1985
M K, Collins, M J, Owen
openaire   +2 more sources

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

TCRdb 2.0: an updated T-cell receptor sequence database. [PDF]

Nucleic Acids Res
Yue T, Chen SY, Shen WK, Liao Y, Lei Q, Guo AY.   +5 more
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Identification of Sjögren's disease-associated T cell receptor motifs through deep sequencing. [PDF]

JCI Insight
Jupudi AA, Joachims ML, Lawrence C, Lopez-Davis C, Khatri B, Rasmussen A, Grundahl K, Scofield RH, James JA, Guthridge JM, Lessard CJ, Thompson LF, Farris AD.   +12 more
europepmc   +1 more source