Results 191 to 200 of about 118,951 (307)

Assessment of Oxidative Stress, Vitellogenin, and Human Health Risks Derived From Nile Tilapia Exposed to Metals and Metalloids in Southeastern Brazil

Environmental Toxicology, EarlyView.
ABSTRACT Urban coastal lagoons are highly vulnerable ecosystems increasingly affected by metal contamination, as well as multiple anthropogenic stressors. This study evaluated ecotoxicological and human health risks associated with chronic metal exposure in Nile tilapia (Oreochromis niloticus) from an anthropogenically impacted lagoon in southeastern ...
Julia Araújo Alves, Priscila M. O. Muniz Cunha, Shênia Patrícia Corrêa Novo, Lorena Oliveira Souza Soares, Tatiana Dillenburg Saint‐Pierre, Fábio Veríssimo Correia, André Luís de Sá Salomão, Rachel Ann Hauser‐Davis, Enrico Mendes Saggioro   +8 more
wiley   +1 more source

Distinct T-cell receptor (TCR) gene segment usage and MHC-restriction between foetal and adult thymus. [PDF]

Elife
Rowell J, Lau CI, Ross S, Yanez DC, Peña OA, Chain B, Crompton T.   +6 more
europepmc   +1 more source

Clonally expanded alpha-chain T-cell receptor (TCR) transcripts are present in aneurysmal lesions of patients with Abdominal Aortic Aneurysm (AAA). [PDF]

PLoS One, 2019
Lu S, White JV, Judy RI, Merritt LL, Lin WL, Zhang X, Solomides C, Nwaneshiudu I, Gaughan J, Monos DS, Oleszak EL, Platsoucas CD.   +11 more
europepmc   +1 more source

Enhancement of immune checkpoint inhibitor efficacy by DHX58+ SELL+ T cells in advanced gastric cancer

VIEW, EarlyView.
We created a coculture system using patient‐derived organoids (PDOs) and tumor‐infiltrating lymphocytes (TILs) that mimics important interactions between PDOs and TILs in the presence of various ICIs. Our findings reveal that CD62L+ T cells, activated by CD44+ cancer stem cells (CSCs), facilitate tumor regression in samples sensitive to ICIs, which is ...
Jie Chen, Youdong Liu, Hongda Pan, Tianyi Cai, Mingde Zang, Xiaowen Liu, Ziwen Long, Xin Fan, Jun Lu, Fenglin Liu   +9 more
wiley   +1 more source

T-cell Receptor (TCR)-Vβ Repertoire Flow Cytometry for T-cell Lymphoproliferative Disorder: a Retrospective Analysis of a Single-Center Real-Life Laboratory Experience. [PDF]

Mediterr J Hematol Infect Dis
Antonacci M, Micozzi J, Costa A, Laganà A, Milani ML, Intoppa S, Bellomarino V, Nardacci MG, Biglietto M, Imperatore S, Bisegna ML, Martelli M, Della Starza I, De Propris MS.   +13 more
europepmc   +1 more source

The natural sesquiterpene lactones arglabin, grosheimin, agracin, parthenolide, and estafiatin inhibit T cell receptor (TCR) activation. [PDF]

Phytochemistry, 2018
Schepetkin IA, Kirpotina LN, Mitchell PT, Kishkentaeva АS, Shaimerdenova ZR, Atazhanova GA, Adekenov SM, Quinn MT.   +7 more
europepmc   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

Development and characterization of human T-cell receptor (TCR) alpha and beta clones' library as biological standards and resources for TCR sequencing and engineering. [PDF]

Biol Methods Protoc
Wei YC, Pospiech M, Meng Y, Alachkar H.
europepmc   +1 more source

Mapping the Radiopharmaceutical Therapy Landscape for Prostate Cancer: Insights Into Global Clinical Trial Trends and Future Directions

Med Research, EarlyView.
Zhiwu Dong, Sixiang Yan, Xiaodong Liu, Peng Gu   +3 more
wiley   +1 more source