Results 201 to 210 of about 1,946,426 (304)

Functional–Taxonomic Scaling Resolves Conflicting Average Genome Size Estimates Across Environmental Gradients

Advanced Science, EarlyView.
Based on genome size‐functional breadth theory, we introduce and validate a framework that adjudicates conflicting average genome size (AGS) estimates by testing which estimate yields a gap between scaled functional diversity and scaled taxonomic diversity that is consistent with the expected positive association between genome size and gene functional
Huanhuan Zhu, Xiaoye Chen, Qiushi Li, Chenyu Sun, Haihua Xia, Yingxin Huang, Cong Wang, Peilin Chen, Cheng Gao   +8 more
wiley   +1 more source

NK- and T-cell repertoire is established early after allogeneic HSCT and is imprinted by CMV reactivation. [PDF]

Blood Adv
Schäfer A, Calderin Sollet Z, Hervé MP, Buhler S, Ferrari-Lacraz S, Norman PJ, Kichula KM, Farias TDJ, Masouridi-Levrat S, Mamez AC, Pradier A, Simonetta F, Chalandon Y, Villard J.   +13 more
europepmc   +1 more source

T cell repertoire following autologous stem cell transplantation for multiple sclerosis.

Journal of Clinical Investigation, 2014
P. Muraro, H. Robins, Sachin Malhotra, M. Howell, D. Phippard, Cindy Desmarais, Alessandra de Paula Alves Sousa, Linda M. Griffith, N. Lim, R. Nash, L. Turka   +10 more
semanticscholar   +1 more source

Phase Separation of SF3B1 Serves as a Critical Post‐Transcriptional Regulator During Early Mouse Embryogenesis

Advanced Science, EarlyView.
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao, Ting‐Yu Han, Yan‐Li Cheng, Yi‐Dan Zhang, Yu‐Wei Zhang, JinJian Guo, ShaoJun Zhang, WenZe Huang, Jing Zhang, Pei‐Yu Liao, Ying Xin, ChuanChen Chu, Qing‐Yuan Sun, ZhiZhen Liu, Xiang‐Hong Ou, Jun Xie   +15 more
wiley   +1 more source

Genomic and T cell repertoire biomarkers associated with malignant mesothelioma survival. [PDF]

Thorac Cancer
Nie M, Sun Z, Li N, Zhou L, Wang S, Yuan M, Chen R, Zhao L, Li J, Bai C.   +9 more
europepmc   +1 more source

Single‐Cell Profiling Reveals Clonally Expanded CX3CR1+ T Cells in Anti‐NMDA Receptor Encephalitis

Advanced Science, EarlyView.
CX3CR1+ T cells are associated with peripheral and central immune alterations in anti‐NMDA receptor encephalitis (NMDAR‐E). They show potential responsiveness to GluN1 (NR1) peptides, potential interactions with peripheral B cells, clonal expansion, increased CD137/CD154 expression, and inflammatory cytokine production. Their preferential cerebrospinal
Lin Yan, Erdi Zhang, Yuwen Ma, Zirui Meng, Sisi Li, Yimeng Ren, Xiaohe Tian, Yangyi He, Giuseppe Battaglia, Dong Zhou, Yun Liao, Binwu Ying, Jinmei Li, Minjin Wang   +13 more
wiley   +1 more source

The endogenous antigen-specific CD8⁺ T cell repertoire is composed of unbiased and biased clonotypes with differential fate commitments. [PDF]

Immunity
Abdullah L, Emiliani FE, Vaidya CM, Stuart H, Musial SC, Kolling FW, Obar JJ, Rosato PC, Ackerman ME, Song L, McKenna A, Huang YH.   +11 more
europepmc   +1 more source

FTSJ3‐Mediated 2′‐O‐Methylation of HSPA5 mRNA Stabilizes BOP1 via SUMOylation to Drive DRP1‐Dependent Mitochondrial Fission and Fatty Acid Oxidation in Lung Squamous Cell Carcinoma

Advanced Science, EarlyView.
The RNA methyltransferase FTSJ3 drives lung squamous cell carcinoma progression by catalyzing 2′‐O‐methylation of HSPA5 mRNA, which stabilizes BOP1 through SUMOylation and activates DRP1/SREBP1‐mediated mitochondrial fission and fatty acid oxidation. Targeting this axis with liposomal siRNA potently suppresses tumor growth and metastasis ABSTRACT Lung ...
Qin Hu, Jiaheng Lin, Yifei Zhu, Ying Liu, Guoren Zhou   +4 more
wiley   +1 more source

Corrigendum: A Comprehensive Analysis of the T and B Lymphocytes Repertoire Shaped by HIV Vaccines

Frontiers in Immunology, 2018
Longlong Wang, Longlong Wang, Longlong Wang, Wei Zhang, Wei Zhang, Liya Lin, Liya Lin, Xiao Li, Xiao Li, Nitin K. Saksena, Nitin K. Saksena, Jinghua Wu, Jinghua Wu, Shiyu Wang, Shiyu Wang, Shiyu Wang, Joseph G. Joyce, Xiuqing Zhang, Xiuqing Zhang, Huanming Yang, Huanming Yang, Jian Wang, Jian Wang, I-Ming Wang, Xiao Liu, Xiao Liu   +25 more
doaj   +1 more source

Unraveling the chicken T cell repertoire with enhanced genome annotation. [PDF]

Front Immunol
Früh SP, Früh MA, Kaufer BB, Göbel TW.   +3 more
europepmc   +1 more source