SPP1 + macrophages cause exhaustion of tumor-specific T cells in liver metastases. [PDF]
Trehan R+14 more
europepmc +1 more source
Characterization of Feline T- and B-Lymphocytes and Identification of an Experimentally Induced T-Cell Neoplasm in the Cat23 [PDF]
Gary L. Cockerell+4 more
openalex +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source
Gamma delta T cells and their immunotherapeutic potential in cancer. [PDF]
Cieslak SG, Shahbazi R.
europepmc +1 more source
The role of H-2-linked genes in helper T-cell function. III. Expression of immune response genes for trinitrophenyl conjugates of poly-L(Tyr, Glu)-poly-D,L-Ala--poly-L-Lys in B cells and macrophages. [PDF]
Philippa Marrack, J W Kappler
openalex +1 more source
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini+10 more
wiley +1 more source
Exploring the role of T cells in Alzheimer's and other neurodegenerative diseases: Emerging therapeutic insights from the T Cells in the Brain symposium. [PDF]
Elyaman W+18 more
europepmc +1 more source
Thermolabile T (tumor) antigen from cells transformed by a temperature-sensitive mutant of simian virus 40. [PDF]
Daniel G. Tenen+2 more
openalex +1 more source
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan+10 more
wiley +1 more source