Results 301 to 310 of about 27,710,413 (387)

Data Sheet 1_Compensatory mechanisms in γδ T cell-deficient chickens following Salmonella infection.docx

Felix Tetzlaff (10585235), Ulrich Methner (129018), Theresa von Heyl (21358229), Christian Menge (580387), Benjamin Schusser (488608), Angela Berndt (185986)   +5 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Possible Involvement of Skin-Resident Memory T Cells in Refractory Chronic Alopecia Areata. [PDF]

Exp Dermatol
Kageyama R, Ito T, Kurihara K, Fujiyama T, Honda T.   +4 more
europepmc   +1 more source

BiomoleculeConjugation Strategy for HAGM Cryogelsto Create 3D Immune Niches that Induce Multifunctional T Cells

Marjolein Schluck (6836780), Jorieke Weiden (6016520), Roel Hammink (1651546), Lea Weiss (16405790), M. Eloisa Vega Quiroz (21747403), Maren Pfirrmann (21747406), Laia Junquera Guinovart (21747409), Vincent van der Steen (21747412), Chadia Archidi (21747415), Leanne H. Minall (21747418), René Classens (18499040), Mahboobeh Rezaeeyazdi (11647675), Thibault Colombani (2565103), Sidi A. Bencherif (2267545), Carl G. Figdor (88844), Martijn Verdoes (195312)   +15 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Circulating Neoantigen- and Viral Oncoprotein-Specific CD8+ T Cells Share a Transcriptional Signature. [PDF]

Cancer Immunol Res
Jani S, Bencomo T, Shasha C, Pulliam T, Jojic A, Church CD, Gooley TA, Koelle DM, Newell EW, Nghiem P.   +9 more
europepmc   +1 more source

Age of the CD8 + T cells recruited into the memory inflation response dictates phenotype.

Zachary T. Hilt (20968584), Arnold Reynaldi (3167352), Megan Steinhilber (21800216), Shide Zhang (676698), Samantha P. Wesnak (21800219), Norah L. Smith (457833), Miles P. Davenport (8201889), Brian D. Rudd (21800222)   +7 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Optogenetic control of T cells for immunomodulation. [PDF]

Essays Biochem
McKee B, Liu S, Cai PX, Yang Z, Lan TH, Zhou Y.   +5 more
europepmc   +1 more source