Results 221 to 230 of about 42,893 (255)

A successful in vitro fertilization outcome in a hermaphrodite male

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 424-425, April 2025.
Shima Elbakhit M. E. Albasha, Sami Saadi Al‐Said, Haitham Tharwat M. H. El Bardisi   +2 more
wiley   +1 more source

Differentiation of human T follicular helper cells in vitro requires co-operation between STAT3 and SMAD signaling cytokines that is restrained by IL-2

Foster WS, Labeur-Iurman L, Williams GS, Robinson MJ, Carlesso G, Lloyd CM, Harker JA.   +6 more
europepmc   +1 more source

Follicular Helper T Cells

Annual Review of Immunology, 2016
Although T cell help for B cells was described several decades ago, it was the identification of CXCR5 expression by B follicular helper T (Tfh) cells and the subsequent discovery of their dependence on BCL6 that led to the recognition of Tfh cells as an independent helper subset and accelerated the pace of discovery. More than 20 transcription factors,
Michelle Linterman, Vinuesa Cg, Di Yu
exaly   +6 more sources

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T follicular helper cells and T follicular regulatory cells in rheumatic diseases

Nature Reviews Rheumatology, 2019
As a hallmark of autoimmune rheumatic diseases, autoantibodies have been used in diagnosis for decades. However, the immunological mechanism underlying their generation has only become clear following the identification of T follicular helper (TFH) cells and T follicular regulatory (TFR) cells. TFH cells are instrumental in supporting antibody affinity
Valter R Fonseca, Luis Graça, Jun Deng   +2 more
exaly   +6 more sources

Revealing T follicular helper cells with BCL6

Nature Reviews Immunology, 2021
Shane Crotty discusses three independent studies published in 2009 that characterized T follicular helper cells as a distinct subset of CD4+ T cells on the basis of selective expression of BCL6.
Shane Crotty, Crotty Shane
exaly   +3 more sources

T follicular helper cells in space-time

Nature Reviews Immunology, 2016
T follicular helper (TFH) cells play a crucial part in the development of humoral immunity by controlling the formation of, and the cellular reactions that occur in, germinal centres. Within these organized lymphoid tissue microstructures, B cells proliferate and somatically mutate to produce long-lived, high-affinity plasma cells and memory B cells ...
Hai Qi, Qi Hai
exaly   +3 more sources

Follicular T helper cells and cutaneous T-cell lymphomas

British Journal of Dermatology, 2022
Abstract Linked Article:  Wang et al. Br J Dermatol 2022; 187:970–980.
openaire   +2 more sources

T follicular helper cells in autoimmune diseases

Journal of Autoimmunity, 2023
T follicular helper (Tfh) cells with the phenotype of mainly expressing surface molecules C-X-C motif chemokine receptor type 5 (CXCR5), inducible co-stimulator (ICOS), secreting cytokine interleukin-21 (IL-21) and requiring the transcription factor B cell lymphoma 6 (BCL-6) have been recently defined as a new subset of CD4+ T cells.
Xindi Wei, Xiaoyin Niu
openaire   +2 more sources

Follicular helper T cells in rheumatoid arthritis

Clinical Rheumatology, 2015
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation in the joints and other tissues. Rheumatoid factor (RF) and anticyclic citrullinated peptides (anti-CCP) are biomarkers for the evaluation of RA although their functions in the pathogenesis of RA are poorly understood.
Meixing, Yu, Vanesssa, Cavero, Qiao, Lu, Hong, Li   +3 more
openaire   +2 more sources

Noncanonical functions of T follicular helper cells

Science Immunology
T follicular helper cells (T FH cells) are essential for germinal center (GC) formation and maintenance. However, recent insights reveal that T FH cells play additional immune regulatory roles beyond their traditional B cell helper function.
Shivangi Dave, André Ballesteros-Tato
openaire   +2 more sources