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Suppressor T‐Lymphocytes in Pregnancy
American Journal of Reproductive Immunology, 1984 ABSTRACT: Primiparous and multiparous healthy pregnant women were tested at the end of the gestation period, or immediately after delivery, for their lymphocyte reactivity to paternal or neonatal cells in mixed lymphocyte culture and in cell‐mediate cytotoxicity assays.
Vanderbeeken, Y.E. +3 more
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The International Journal of Biochemistry & Cell Biology, 2003
T cells are major players in the adaptive immune response to pathogens. They express clonally distributed, highly polymorphic antigen receptors that enable them to recognize cell-associated antigen. Upon antigen recognition, T cells undergo clonal amplification and progressively acquire effector functions, ranging from the production of paracrine ...
FABBRI M, SMART C, PARDI , RUGGERO
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T cells are major players in the adaptive immune response to pathogens. They express clonally distributed, highly polymorphic antigen receptors that enable them to recognize cell-associated antigen. Upon antigen recognition, T cells undergo clonal amplification and progressively acquire effector functions, ranging from the production of paracrine ...
FABBRI M, SMART C, PARDI , RUGGERO
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Scandinavian Journal of Gastroenterology, 1995
The intestine is largely colonized by bacteria and further exposed to an immense array of ingested and shed immunogenic material. Therefore, the gut associated lymphoid tissue plays a major role in the human immune system. It may even constitute a unique immune system of its own, since it has been demonstrated to differ anatomically, phenotypically ...
R J, Robijn +5 more
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The intestine is largely colonized by bacteria and further exposed to an immense array of ingested and shed immunogenic material. Therefore, the gut associated lymphoid tissue plays a major role in the human immune system. It may even constitute a unique immune system of its own, since it has been demonstrated to differ anatomically, phenotypically ...
R J, Robijn +5 more
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The Activation of T Lymphocytes
Rheumatic Disease Clinics of North America, 1987The events involved in T cell activation are initiated at the cell surface by the interaction of ligands with specific cell surface receptors on the T cell. Central to antigen-induced activation is the CD3/Ti complex, a complex multi-chain receptor responsible for antigen/MHC recognition and signal transduction. Triggering the CD3/Ti complex results in
L K, Bockenstedt +3 more
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Annual Review of Immunology, 1983
observations and their interpretation becomes blurred with time. A re-evaluation of the data on CTL may become important at a time when the emphasis of the questions asked about these cells changes. We think the discovery of T-cell growth factor and the design of methods that have allowed the maintenance of CTL clones in permanent culture have ushered ...
M, Nabholz, H R, MacDonald
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observations and their interpretation becomes blurred with time. A re-evaluation of the data on CTL may become important at a time when the emphasis of the questions asked about these cells changes. We think the discovery of T-cell growth factor and the design of methods that have allowed the maintenance of CTL clones in permanent culture have ushered ...
M, Nabholz, H R, MacDonald
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Annual Review of Immunology, 1983
To date, the most successful uses of T-cell clones have been in the demonstration that a single type of cell can perform multiple functions. However, their potential usefulness is enormous, and the study of cell interactions using clonal populations has just begun.
C G, Fathman, J G, Frelinger
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To date, the most successful uses of T-cell clones have been in the demonstration that a single type of cell can perform multiple functions. However, their potential usefulness is enormous, and the study of cell interactions using clonal populations has just begun.
C G, Fathman, J G, Frelinger
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Cellular and Molecular Life Sciences CMLS, 1999
Immunological memory protects organisms from recurrent challenge by pathogens. The persistence of a heightened reactive state initiated by antigenic challenge is mediated by long-lived memory lymphocytes. The survival of memory T cells is thought to require stimulation through the T cell receptor (TCR), sometimes by persistent antigen.
P G, Ashton-Rickardta, J T, Opferman
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Immunological memory protects organisms from recurrent challenge by pathogens. The persistence of a heightened reactive state initiated by antigenic challenge is mediated by long-lived memory lymphocytes. The survival of memory T cells is thought to require stimulation through the T cell receptor (TCR), sometimes by persistent antigen.
P G, Ashton-Rickardta, J T, Opferman
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Rheumatic Disease Clinics of North America, 2004
T cells constitute one arm of the adaptive immune system. The accumulating information on various aspects of T-cell biology shows the intricacies in the regulation of immune responses. How we translate the cellular and molecular details of this regulation into innovation and development of therapies for disease management remains a fundamental, but ...
Abbe N, Vallejo +3 more
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T cells constitute one arm of the adaptive immune system. The accumulating information on various aspects of T-cell biology shows the intricacies in the regulation of immune responses. How we translate the cellular and molecular details of this regulation into innovation and development of therapies for disease management remains a fundamental, but ...
Abbe N, Vallejo +3 more
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International Archives of Allergy and Immunology, 2009
Some of the key features of aging effects on T lymphocytes have been illuminated in the last few years from new angles. Experimental evidence indicates a profound increase in the proportion of memory versus naive types of T cells, a decline in the response to activation and in the capacity to enter the cycle, and decline in levels of IL-2, yet an ...
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Some of the key features of aging effects on T lymphocytes have been illuminated in the last few years from new angles. Experimental evidence indicates a profound increase in the proportion of memory versus naive types of T cells, a decline in the response to activation and in the capacity to enter the cycle, and decline in levels of IL-2, yet an ...
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Annales de l'Institut Pasteur / Immunologie, 1983
We have provided a speculative overview of some of the questions concerning the nature of thymic stem cells and the role of the thymus in their maturation, and have suggested experimental approaches which might provide solutions to some of the questions.
J J, Owen, E J, Jenkinson, R, Kingston
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We have provided a speculative overview of some of the questions concerning the nature of thymic stem cells and the role of the thymus in their maturation, and have suggested experimental approaches which might provide solutions to some of the questions.
J J, Owen, E J, Jenkinson, R, Kingston
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