Results 21 to 30 of about 12,046,757 (352)

Cytotoxic T Lymphocytes in Rasmussen’s Encephalitis

Pediatric Neurology Briefs, 2002
The role of cytotoxic T lymphocytes and other mechanisms in the pathogenesis of Rasmussen’s encephalitis (RE) is reviewed at the University of Vienna, Austria, and the University of Bonn, Germany.
J Gordon Millichap
doaj   +1 more source

Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes

Journal of Experimental Medicine, 2017
Activation of the cyclic dinucleotide sensor stimulator of interferon (IFN) genes (STING) is critical for IFN and inflammatory gene expression during innate immune responses. However, the role of STING in adaptive immunity is still unknown. In this study,
S. Cerboni, N. Jeremiah, M. Gentili, U. Gehrmann, Cécile Conrad, M. Stolzenberg, C. Picard, B. Neven, A. Fischer, S. Amigorena, F. Rieux-Laucat, N. Manel   +11 more
semanticscholar   +1 more source

Lipoprotein(a), its autoantibodies, and circulating T lymphocyte subpopulations as independent risk factors for coronary artery atherosclerosis [PDF]

Терапевтический архив, 2016
Aim. To study the role of lipoprotein(a) [Lp(a)] as a potential autoantigen causing the activation of immunocompetent cells in atherosclerosis. Subjects and methods.
O I Afanasievа, E A Pylaeva, E A Klesareva, A V Potekhina, S I Provatorov, M I Afanasieva, T L Krasnikova, V P Masenko, T I Arefieva, S N Pokrovsky   +9 more
doaj   +1 more source

Colorectal cancer-infiltrating T lymphocytes display a distinct chemokine receptor expression profile

European Journal of Medical Research, 2017
Background T lymphocytes exert important homeostatic functions in the healthy intestinal mucosa, whereas in case of colorectal cancer (CRC), infiltration of T lymphocytes into the tumor is crucial for an effective anti-tumor immune response.
Ann-Britt Löfroos, Mohammad Kadivar, Sabina Resic Lindehammer, Jan Marsal   +3 more
doaj   +1 more source

Intratumoural immune signature to identify patients with primary colorectal cancer who do not require follow-up after resection: an observational study

Health Technology Assessment, 2021
Background: Following surgical and adjuvant treatment of primary colorectal cancer, many patients are routinely followed up with axial imaging (most commonly computerised tomography imaging) and blood carcinoembryonic antigen (a tumour marker) testing ...
John N Primrose, Siân A Pugh, Gareth Thomas, Matthew Ellis, Karwan Moutasim, David Mant   +5 more
doaj   +1 more source

Role of the cellular immunity in the formation of the immune response in coronavirus infections

Медицинская иммунология, 2021
The data obtained during previous epidemics caused by coronaviruses, and current pandemic indicate that assessing the role of certain immune interactions between these viruses and the microorganism is the main pre-requisite for development of diagnostic ...
I. A. Ivanova, N. D. Omelchenko, A. V. Filippenko, A. A. Trufanova, A. K. Noskov   +4 more
doaj   +1 more source

B lymphocytes secrete antigen-presenting vesicles

Journal of Experimental Medicine, 1996
Antigen-presenting cells contain a specialized late endocytic compartment, MIIC (major histocompatibility complex [MHC] class II- enriched compartment), that harbors newly synthesized MHC class II molecules in transit to the plasma membrane. MIICs have a
G. Raposo, H. Nijman, W. Stoorvogel, R. Liejendekker, C. Harding, C. Melief, H. Geuze   +6 more
semanticscholar   +1 more source

Characteristics of T-cell immunity and level of the natural killer cells content in COVID-19 convalescents with carbohydrate metabolism disorders

Медицинская иммунология, 2023
The pandemic of the new COVID-19 coronavirus infection has created a public health emergency in the Russian Federation in 2020-2022. COVID-19 causes various consequences, often manifested by the endocrine system dysfunction.
K. S. Savchuk
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Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T-lymphocytes

Nature Medicine, 2015
Adoptive transfer of chimeric antigen receptor (CAR)-redirected T lymphocytes (CAR-T cells) has had less striking therapeutic effects in solid tumors than in lymphoid malignancies.
Ignazio Caruana, B. Savoldo, V. Hoyos, G. Weber, Hao Liu, Eugene S. Kim, M. Ittmann, D. Marchetti, G. Dotti   +8 more
semanticscholar   +1 more source

Production of CD87 Antigen-Specific CAR-T Lymphocytes and Assessment of Their In Vitro Functional Activity

Клиническая онкогематология, 2022
Aim. To generate anti-CD87 CAR-T lymphocytes and to assess their in vitro functional activity. Materials & Methods. Т-lymphocytes isolated from healthy donor peripheral blood were transduced with the anti-CD87-CAR, T2A, and FusionRed gene coding ...
M. V. Neklesova, Sergei Vladimirovich Smirnov, A. A. Shatilova, K. A. Levchuk, A. E. Ershova, S. A. Silonov   +5 more
doaj   +1 more source