Results 31 to 40 of about 12,899,769 (365)

B lymphocytes secrete antigen-presenting vesicles

Journal of Experimental Medicine, 1996
Antigen-presenting cells contain a specialized late endocytic compartment, MIIC (major histocompatibility complex [MHC] class II- enriched compartment), that harbors newly synthesized MHC class II molecules in transit to the plasma membrane. MIICs have a
G. Raposo, H. Nijman, W. Stoorvogel, R. Liejendekker, C. Harding, C. Melief, H. Geuze   +6 more
semanticscholar   +1 more source

Intratumoural immune signature to identify patients with primary colorectal cancer who do not require follow-up after resection: an observational study

Health Technology Assessment, 2021
Background: Following surgical and adjuvant treatment of primary colorectal cancer, many patients are routinely followed up with axial imaging (most commonly computerised tomography imaging) and blood carcinoembryonic antigen (a tumour marker) testing ...
John N Primrose, Siân A Pugh, Gareth Thomas, Matthew Ellis, Karwan Moutasim, David Mant   +5 more
doaj   +1 more source

Role of the cellular immunity in the formation of the immune response in coronavirus infections

Медицинская иммунология, 2021
The data obtained during previous epidemics caused by coronaviruses, and current pandemic indicate that assessing the role of certain immune interactions between these viruses and the microorganism is the main pre-requisite for development of diagnostic ...
I. A. Ivanova, N. D. Omelchenko, A. V. Filippenko, A. A. Trufanova, A. K. Noskov   +4 more
doaj   +1 more source

Classification of T lymphocyte motility behaviors using a machine learning approach.

PLoS Computational Biology, 2023
T lymphocytes migrate into organs and interact with local cells to perform their functions. How human T lymphocytes communicate with organ-specific cells and participate in pathobiological processes remains unresolved. Brain infiltration of T lymphocytes
Yves Carpentier Solorio, Florent Lemaître, Bassam Jabbour, Olivier Tastet, Nathalie Arbour, Elie Bou Assi   +5 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

FEATURES OF THE PHENOTYPE OF REGULATORY T CELLS IN EARLY AND ADVANCED RHEUMATOID ARTHRITIS

Научно-практическая ревматология, 2018
Objective: to analyze the levels of CD3+, CD3+CD4+, CD3+CD8+, and CD3-CD56+ T lymphocytes, FoxP3+ regulatory T cells (Treg), and CD19+ B lymphocytes in patients with early and advanced rheumatoid arthritis (RA). Subjects and methods.
A. S. Avdeeva, Yu. P. Rubtsov, T. V. Popkova, D. T. Dyikanov, A. P. Aleksankin, E. L. Nasonov   +5 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Dynamic assessment of T-lymphocytes and humoral immunity in patients with acute coronary syndrome, with and without COVID-19, depending on the content of CD3⁺CD8⁺T-lymphocytes

Медицинский вестник Юга России
Objective: to evaluate the dynamics of the T- and B-cell immunity in patients with acute coronary syndrome (ACS) who have and have not had COVID-19, depending on the number of CD3+CD8+T-lymphocytes.Materials and methods: 65 men with ACS who underwent ...
E. A. Safronova, L. V. Ryabova, A. V. Zurochka, M. A. Dobrynina, E. V. Zadorina   +4 more
doaj   +1 more source

Local CD4+, CD8+ and CD56+ reactions to lung cancer in regard to pathohistological type and clinical stage [PDF]

Medicinski Glasnik, 2011
Aim To determinate the difference of abundance of CD4+, CD8+ and CD56+ bronchoalveolar luid’s lymphocytes and their subpopulations between non- and small cell lung cancer.
Edin Jusufovic, Ermina Iljazovic, Mitja Kosnik, Dragan Keser, Peter Korosec, Edin Zukic, Besim Prnjavorac, Rifat Sejdinović, Ekrem Ajanović   +8 more
doaj  

B-Lymphocyte Phenotype Determines T-Lymphocyte Subset Differentiation in Autoimmune Diabetes

Frontiers in Immunology, 2019
Previous studies indicate that B-lymphocytes play a key role activating diabetogenic T-lymphocytes during the development of autoimmune diabetes. Recently, two transgenic NOD mouse models were generated: the NOD-PerIg and the 116C-NOD mice.
Leire Egia-Mendikute, Berta Arpa, Estela Rosell-Mases, Marta Corral-Pujol, Jorge Carrascal, Jorge Carrillo, Conchi Mora, Harold Chapman, Anaïs Panosa, Marta Vives-Pi, Marta Vives-Pi, Thomas Stratmann, David Serreze, Joan Verdaguer, Joan Verdaguer   +14 more
doaj   +1 more source