Results 41 to 50 of about 1,131,184 (349)

Natalizumab affects T-cell phenotype in multiple sclerosis: implications for JCV reactivation [PDF]

, 2016
The anti-CD49d monoclonal antibody natalizumab is currently an effective therapy against the relapsing-remitting form of multiple sclerosis (RRMS). Natalizumab therapeutic efficacy is limited by the reactivation of the John Cunningham polyomavirus (JCV ...
A Bellizzi, A Laroni, A Petrovic, Ada Francia, Alessandra D’Abramo, Alessandra Oliva, Anna Bellizzi, B Engelhardt, BL Padgett, C Bozic, C Tornatore, Claudia D’Agostino, Claudio Maria Mastroianni, D Jing, E Pucci, Elena Anzivino, EM Frohman, EM Johnson, Enrico Millefiorini, EO Major, EO Major, F Serana, F Taguchi, G Defer, H Bonig, K Khalili, L Börnsen, L Gorelik, LJ Marshall, M Niino, Manuela Morreale, Marco Iannetta, Maria Antonella Zingaropoli, Maria Rosa Ciardi, MC Monaco, ME Hemler, P Maenetje, RA Rudick, RM Ransohoff, Robert Shin Fujinami, RR Lobb, S Beltrami, SA Houff, SA Sadiq, Sara Lo Menzo, Simona Pontecorvo, T Van Loy, Valeria Pietropaolo, Vincenzo Vullo, WJ Atwood, Y Chen, Ö Yaldizli   +51 more
core   +10 more sources

Origin of lymph node-derived lymphocytes in human hepatic allografts [PDF]

, 1989
Hepatic allograft-derived lymph nodes were examined in the post-transplant period on order to determine the origin of lymphocytes and structural elements of the lymph node.
Chen, K, Demetris, AJ, Duquesnoy, RJ, Fung, JJ, Markus, B, Marrarri, M, Starzl, TE, Zeevi, A   +7 more
core   +1 more source

Gamma interferon-dependent clearance of cytomegalovirus infection in salivary glands [PDF]

, 1992
Cytomegalovirus (CMV), similar to other members of the Herpesviridae family, can establish both persistent and latent infections. Each of the CMVs that are found in many animal species replicates in the salivary gland, and oral secretion represents a ...
Jonjic, Stipan, Koszinowski, Ulrich H., Lucin, Pero, Pavic, Ivica, Polic, Bojan   +4 more
core   +2 more sources

What to Do When Medical Evidence Can Only Be Generated Through Routine Data: An Example From Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Children undergoing allogeneic stem cell transplantation often receive off‐label rituximab treatment for Epstein–Barr virus reactivation, using adult dosing without pediatric evidence. This project aims to develop a clinical decision support tool (CDSS) that provides evidence‐based dosing scenarios by analyzing real‐world patient data.
Birgit Burkhardt, Antje Walz, Dietrich Knoerzer   +2 more
wiley   +1 more source

FEATURES OF THE PHENOTYPE OF REGULATORY T CELLS IN EARLY AND ADVANCED RHEUMATOID ARTHRITIS

Научно-практическая ревматология, 2018
Objective: to analyze the levels of CD3+, CD3+CD4+, CD3+CD8+, and CD3-CD56+ T lymphocytes, FoxP3+ regulatory T cells (Treg), and CD19+ B lymphocytes in patients with early and advanced rheumatoid arthritis (RA). Subjects and methods.
A. S. Avdeeva, Yu. P. Rubtsov, T. V. Popkova, D. T. Dyikanov, A. P. Aleksankin, E. L. Nasonov   +5 more
doaj   +1 more source

HLA-DR in Cytotoxic T lymphocytes predicts breast cancer patients' response to neoadjuvant chemotherapy [PDF]

, 2018
Prediction of breast cancer response to Neoadjuvant Chemotherapy (NACT) is an urgent need to promptly direct non-responder patients to alternative therapies.
Borralho, Paula, Braga, Sofia, Cabral, M. Guadalupe, Jacinto, António, Saraiva, Diana P.   +4 more
core   +2 more sources

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

Dynamic assessment of T-lymphocytes and humoral immunity in patients with acute coronary syndrome, with and without COVID-19, depending on the content of CD3⁺CD8⁺T-lymphocytes

Медицинский вестник Юга России
Objective: to evaluate the dynamics of the T- and B-cell immunity in patients with acute coronary syndrome (ACS) who have and have not had COVID-19, depending on the number of CD3+CD8+T-lymphocytes.Materials and methods: 65 men with ACS who underwent ...
E. A. Safronova, L. V. Ryabova, A. V. Zurochka, M. A. Dobrynina, E. V. Zadorina   +4 more
doaj   +1 more source

Local CD4+, CD8+ and CD56+ reactions to lung cancer in regard to pathohistological type and clinical stage [PDF]

Medicinski Glasnik, 2011
Aim To determinate the difference of abundance of CD4+, CD8+ and CD56+ bronchoalveolar luid’s lymphocytes and their subpopulations between non- and small cell lung cancer.
Edin Jusufovic, Ermina Iljazovic, Mitja Kosnik, Dragan Keser, Peter Korosec, Edin Zukic, Besim Prnjavorac, Rifat Sejdinović, Ekrem Ajanović   +8 more
doaj  

B-Lymphocyte Phenotype Determines T-Lymphocyte Subset Differentiation in Autoimmune Diabetes

Frontiers in Immunology, 2019
Previous studies indicate that B-lymphocytes play a key role activating diabetogenic T-lymphocytes during the development of autoimmune diabetes. Recently, two transgenic NOD mouse models were generated: the NOD-PerIg and the 116C-NOD mice.
Leire Egia-Mendikute, Berta Arpa, Estela Rosell-Mases, Marta Corral-Pujol, Jorge Carrascal, Jorge Carrillo, Conchi Mora, Harold Chapman, Anaïs Panosa, Marta Vives-Pi, Marta Vives-Pi, Thomas Stratmann, David Serreze, Joan Verdaguer, Joan Verdaguer   +14 more
doaj   +1 more source