Results 41 to 50 of about 1,057,642 (298)

DR-bearing T lymphocytes in thoracic duct lymph [PDF]

, 1981
T cells having DR antigens were shown to be present in high numbers in the thoracic duct lymph of patients undergoing long-term drainage. As drainage progresses the proportion of T DR cells in the lymph increases to levels as high as 70% at 6 weeks ...
Abo, Albrechtson, Billing, Boyle, Colombani, Evans, Foon, Franksson, Fu, Greaves, H. Takahashi, J.C. Cicciarelli, Johnson, Kaplan, Machleder, Matell, Medawar, P.I. Terasaki, R. Billing, Starzl, Starzl, Suciu-Foca, T. Starzl, T. Yamaguchi, Terasaki, Y. Iwaki   +25 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Production of CD87 Antigen-Specific CAR-T Lymphocytes and Assessment of Their In Vitro Functional Activity

Клиническая онкогематология, 2022
Aim. To generate anti-CD87 CAR-T lymphocytes and to assess their in vitro functional activity. Materials & Methods. Т-lymphocytes isolated from healthy donor peripheral blood were transduced with the anti-CD87-CAR, T2A, and FusionRed gene coding ...
M. V. Neklesova, Sergei Vladimirovich Smirnov, A. A. Shatilova, K. A. Levchuk, A. E. Ershova, S. A. Silonov   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

FEATURES OF THE PHENOTYPE OF REGULATORY T CELLS IN EARLY AND ADVANCED RHEUMATOID ARTHRITIS

Научно-практическая ревматология, 2018
Objective: to analyze the levels of CD3+, CD3+CD4+, CD3+CD8+, and CD3-CD56+ T lymphocytes, FoxP3+ regulatory T cells (Treg), and CD19+ B lymphocytes in patients with early and advanced rheumatoid arthritis (RA). Subjects and methods.
A. S. Avdeeva, Yu. P. Rubtsov, T. V. Popkova, D. T. Dyikanov, A. P. Aleksankin, E. L. Nasonov   +5 more
doaj   +1 more source

Classification of T lymphocyte motility behaviors using a machine learning approach.

PLoS Computational Biology, 2023
T lymphocytes migrate into organs and interact with local cells to perform their functions. How human T lymphocytes communicate with organ-specific cells and participate in pathobiological processes remains unresolved. Brain infiltration of T lymphocytes
Yves Carpentier Solorio, Florent Lemaître, Bassam Jabbour, Olivier Tastet, Nathalie Arbour, Elie Bou Assi   +5 more
doaj   +1 more source

CD4-helper-independent antiviral function of CD8-positive memory T lymphocytes derived from latently infected donors [PDF]

, 1988
The ability of memory T lymphocytes derived from latently infected mice to control murine cytomegalovirus disease in the immunocompromised host was studied by adoptive transfer experiments.
Jonjic, Stipan, Koszinowski, Ulrich H., Mutter, Wolfgang, Reddehase, Matthias J., Weiland, Frank   +4 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Dynamic assessment of T-lymphocytes and humoral immunity in patients with acute coronary syndrome, with and without COVID-19, depending on the content of CD3⁺CD8⁺T-lymphocytes

Медицинский вестник Юга России
Objective: to evaluate the dynamics of the T- and B-cell immunity in patients with acute coronary syndrome (ACS) who have and have not had COVID-19, depending on the number of CD3+CD8+T-lymphocytes.Materials and methods: 65 men with ACS who underwent ...
E. A. Safronova, L. V. Ryabova, A. V. Zurochka, M. A. Dobrynina, E. V. Zadorina   +4 more
doaj   +1 more source

Local CD4+, CD8+ and CD56+ reactions to lung cancer in regard to pathohistological type and clinical stage [PDF]

Medicinski Glasnik, 2011
Aim To determinate the difference of abundance of CD4+, CD8+ and CD56+ bronchoalveolar luid’s lymphocytes and their subpopulations between non- and small cell lung cancer.
Edin Jusufovic, Ermina Iljazovic, Mitja Kosnik, Dragan Keser, Peter Korosec, Edin Zukic, Besim Prnjavorac, Rifat Sejdinović, Ekrem Ajanović   +8 more
doaj