Results 71 to 80 of about 6,764,527 (311)
, 2021 Clinical trials, including chimeric antigen receptor (CAR) T cell therapy for a range of terminal tumors, are now ongoing in several locations across the world, and the commercialization of some of these therapies is likely to begin in the near future.
openaire +1 more source
International mobility of women in science and technology careers: shaping plans for personal and professional purposes [PDF]
, 2017 International mobility has become a key requirement in science and technology (S&T) professional career progression. On the one hand, the increasing mobility of women suggests that this may be a way for them to avoid or get away from women-unfriendly ...
González Ramos, Ana M. +1 more
core +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Knocked out by Rho/Rac T-cell biology [PDF]
, 2012 The Rho/Rac family is a group of Ras-related proteins with demonstrated roles in the regulation of proliferation and cytoskeletal structures in a number of cell lineages.
Bustelo, Xosé R.
core
Quartz technology in Scottish prehistory
Scottish Archaeological Internet Reports, 2016 The project Quartz Technology in Scottish Prehistory was initiated in the year 2000, and over the following five years a large number of quartz assemblages were examined from all parts of Scotland, and from all prehistoric periods. The general aim of the
A. Saville, T. Ballin
semanticscholar +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
International Journal of Physical Sciences, 2012 This paper highlights a comparative study of two new distributed t-way test suite generation strategies, called test suite generator one parameter (TS_OP) and test suite generator one test (TS_OT). Both strategies adopt computational greedy algorithm and were implemented on distributed shared memory environment using Tuple space technology.
openaire +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Fixed and Mobile Phoning in Italian Regions [PDF]
The telecommunication diffusion and it?s interaction with the socio-economic environment was analysed both in terms of introduction of new technologies in the market and their diffusion/substitution process with respect to former technologies ...
Carlo Tesauro +2 more
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source