Results 61 to 70 of about 28,279,407 (312)

Technology Architectural Review [PDF]

, 1887
Publication of the Massachusetts Institute of Technology Architectural Society. Volume 3.
Massachusetts Institute of Technology. Department of Architecture, Massachusetts Institute of Technology. Architectural Society   +1 more
core  

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

THE ATTITUDES OF TEACHERS AND SPECIAL EDUCATORS TOWARDS THE USE OF COMPUTERS AND MODERN TECHNOLOGY IN TEACHING CHILDREN WITH DEVELOPMENTAL DISABILITIES

Research in Education and Rehabilitation
The goal of education is to provide favorable conditions for creativity, cooperation, actualization, and flexibility in order to prepare students for active work and functioning in society. This is especially important for inclusive education as students
Aleksandra Bašić, Dragana Maćešić Pterović, Bojana Arsić   +2 more
doaj   +1 more source

New technologies to improve CAR T cell generation and biomanufacturing will lead to safer, more therapeutically effective cells

, 2021
Clinical trials, including chimeric antigen receptor (CAR) T cell therapy for a range of terminal tumors, are now ongoing in several locations across the world, and the commercialization of some of these therapies is likely to begin in the near future.
openaire   +1 more source

Course Catalogue of the Massachusetts Institute of Technology 2001-2002 [PDF]

, 2001
Massachusetts Institute of Technology Bulletin 2001-2002. Courses and Degree Programs Issue. Includes general information on the Institute; campus life; undergraduate and graduate education; academic procedures and institute regulations ...
​​Massachusetts Institute of Technology
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Course Catalogue of the Massachusetts Institute of Technology 1994-1995 [PDF]

, 1994
Massachusetts Institute of Technology Bulletin 1994-1995. Courses and Degree Programs Issue. Includes general information on the Institute; campus life; undergraduate and graduate education; academic procedures and institute regulations ...
​​Massachusetts Institute of Technology
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‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Course Catalogue of the Massachusetts Institute of Technology 2005-2006 [PDF]

, 2005
Massachusetts Institute of Technology Bulletin 2005-2006. Courses and Degree Programs Issue. Includes general information on the Institute; campus life; undergraduate and graduate education; academic procedures and institute regulations ...
​​Massachusetts Institute of Technology
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source