Identification and characterization of cichlid TAAR genes and comparison with other teleost TAAR repertoires [PDF]
BMC Genomics, 2015 TAARs (trace amine-associated receptors) are among the principal receptors expressed by the olfactory epithelium. We used the recent BROAD Institute release of the genome sequences of five representative fishes of the cichlid family to establish the complete TAAR repertoires of these species and to compare them with five other fish TAAR repertoires.The
Azzouzi, Naoual +2 more
exaly +7 more sources
Chemosensation of the pheromone spermine by the olfactory TAAR-like receptor TAAR348 [PDF]
Cell DiscoveryKexin Jiang +11 more
doaj +6 more sources
Naunyn-Schmiedeberg's Archives of Pharmacology, 2010 Trace amines including tyramine and β-phenylethylamine (β-PEA) increase blood pressure and cause vasoconstriction which is attributed to indirect sympathomimetic actions. However, there is evidence that they may also have non-sympathomimetic mechanisms.
Martina, Fehler +3 more
exaly +5 more sources
Antioxidants, 2022 Atopic dermatitis is regulated by the production of pro-inflammatory cytokines and chemokines via the nuclear factor kappa B or mitogen-activated protein kinase signaling pathways, as well as, the release of oxidative stress-related factors via the NF-E2
Ji-Hyun Lee +5 more
doaj +2 more sources
Molecular Evolution and Functional Divergence of Trace Amine-Associated Receptors. [PDF]
PLoS ONE, 2016 Trace amine-associated receptors (TAARs) are a member of the G-protein-coupled receptor superfamily and are known to be expressed in olfactory sensory neurons. A limited number of molecular evolutionary studies have been done for TAARs so far.
Seong-Il Eyun +3 more
doaj +3 more sources
Olfactory function in the trace amine-associated receptor family (TAARs) evolved twice independently [PDF]
Scientific Reports, 2021 Olfactory receptor families have arisen independently several times during evolution. The origin of taar genes, one of the four major vertebrate olfactory receptor families, is disputed.
Milan Dieris +2 more
doaj +3 more sources
Olfactory expression of trace amine-associated receptors requires cooperative cis-acting enhancers
Nature Communications, 2021 How olfactory sensory neurons express one allele of one TAAR gene is not well understood. Here the authors identify two cooperative cis-acting enhancers that govern TAAR gene choice and that share both similarities and differences with known olfactory ...
Ami Shah +4 more
doaj +2 more sources
Structural and functional evolution of the trace amine-associated receptors TAAR3, TAAR4 and TAAR5 in primates. [PDF]
PLoS ONE, 2010 The family of trace amine-associated receptors (TAAR) comprises 9 mammalian TAAR subtypes, with intact gene and pseudogene numbers differing considerably even between closely related species.
Claudia Stäubert +5 more
doaj +3 more sources
Expression of Neuronal Trace Amine-associated Receptor (Taar) mRNAs in Leukocytes [PDF]
Journal of Neuroimmunology, 2007 Trace amines such as tyramine, octopamine and beta-phenylethylamine bind with high affinity to the mammalian trace amine-associated receptor 1 (Taar1), potentially activating G-proteins in the synaptic membranes of target neurons. Recently there has been significant interest in Taar1, since this receptor can bind certain psychoactive drugs of abuse ...
Daniel A, Nelson +3 more
openaire +4 more sources
Deregulation of Trace Amine-Associated Receptors (TAAR) Expression and Signaling Mode in Melanoma [PDF]
Biomolecules, 2022 Trace amine-associated receptors (TAARs) interact with amine compounds called “trace amines” which are present in tissues at low concentrations. Recently, TAARs expression in neoplastic tumors was reported. In this study, TAARs expression was analyzed in
Anastasia N. Vaganova +3 more
doaj +3 more sources