A potential role for trace amines in the treatment of septic shock [PDF]
Journal of Intensive MedicineSepsis involves an unregulated response to bacterial infection, the inflammatory response leading to persistent hypotension, leading to a precipitous fall in arterial blood pressure. The major trigger for the hypotension in sepsis and septic shock is the
Kenneth J. Broadley +3 more
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Trace Amines and the Trace Amine-Associated Receptor 1: Pharmacology, Neurochemistry and Clinical Implications [PDF]
Frontiers in Neuroscience, 2016 Biogenic amines are a collection of endogenous molecules that play pivotal roles as neurotransmitters and hormones. In addition to the classical biogenic amines resulting from decarboxylation of aromatic acids, including dopamine (DA), norepinephrine ...
Yue ePei +2 more
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Gut microbiota dysbiosis and aromatic amino acid metabolism alterations: a multi-omics analysis of cognitive impairment following aneurysmal subarachnoid hemorrhage [PDF]
Frontiers in MicrobiologyBackgroundAneurysmal subarachnoid hemorrhage (aSAH) is frequently followed by persistent cognitive impairment, characterized by a complex and multifactorial pathological mechanism.
Wentian Zhang +10 more
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Trace Amine-Associated Receptors’ Role in Immune System Functions
BiomedicinesTrace amines are a separate, independent group of biogenic amines, close in structure to classical monoamine neurotransmitters such as dopamine, serotonin, and norepinephrine that include many products of the endogenous or bacteria-mediated ...
Vyacheslav I. Moiseenko +3 more
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Potential contributions of trace amines in Alzheimer’s disease and therapeutic prospects [PDF]
Neural Regeneration Research, 2021 Sudip Dhakal, Ian Macreadie
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Trace amines and their relevance to psychiatry and neurology: a brief overview
Psychiatry and Clinical Psychopharmacology, 2021 The arylalkylamines, β-phenylethylamine, m- and p-tyramine, tryptamine, m- and p-octopamine, phenylethanolamine and synephrine, have been termed trace amines because of their low absolute concentrations in the central nervous system relative to the ...
Deepak Narang +4 more
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Natural Sympathomimetic Drugs: From Pharmacology to Toxicology
Biomolecules, 2022 Sympathomimetic agents are a group of chemical compounds that are able to activate the sympathetic nervous system either directly via adrenergic receptors or indirectly by increasing endogenous catecholamine levels or mimicking their intracellular ...
Vera Marisa Costa +7 more
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Biomolecules, 2023 Currently, the contribution of trace amine-associated receptors (TAARs) to breast cancer (BC) is recognized, but their associations with various pathological characteristics are not yet understood.
Anastasia N. Vaganova +4 more
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Structural and functional evolution of the trace amine-associated receptors TAAR3, TAAR4 and TAAR5 in primates. [PDF]
PLoS ONE, 2010 The family of trace amine-associated receptors (TAAR) comprises 9 mammalian TAAR subtypes, with intact gene and pseudogene numbers differing considerably even between closely related species.
Claudia Stäubert +5 more
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