Results 71 to 80 of about 1,649 (192)

G Protein–Coupled Receptors in Olfactory Signaling and Related Disorders: Mechanisms and Therapeutic Implications

open access: yesSensory Neuroscience, Volume 2, Issue 1, March 2026.
This schematic highlights GPCRs as the central hub of olfactory signaling in health and disease. The central GPCR shows odorant activation and downstream pathways. Surrounding quadrants illustrate four GPCR‐mediated themes: odor perception and adaptation, mucosal immunity and regeneration, memory consolidation via neural circuits, and GPCR‐related ...
Zishuo Guo   +11 more
wiley   +1 more source

Caring for Children With Developmental and Behavioral Disorders: Impact of a Developmental Outreach Clinic Within a Primary Care Setting

open access: yesJournal of Policy and Practice in Intellectual Disabilities, Volume 23, Issue 1, March 2026.
ABSTRACT To evaluate the impact of implementing a Developmental Outreach Clinic within a primary care practice, we implemented a Developmental Outreach Clinic that involved relocating 2 developmental pediatricians to a primary care practice for one half day per week to conduct developmental assessments and consultations on‐site.
Elizabeth Young   +6 more
wiley   +1 more source

Spawning Time of Sandfish, Holothuria scabra in Taar Village

open access: yesAgrikan Jurnal Agribisnis Perikanan
Sandfish, Holothuria scabra is a marine commodity that is exported as a high-value food ingredient, medicinal ingredient and cosmetic ingredient. Sandfish cultivation has begun to be developed intensively in Tual City, Maluku. Breeding and spawning are key factors supporting intensive sandfish cultivation. This study aims to determine the spawning time
Pitjont Tomatala   +2 more
openaire   +1 more source

The sea lamprey Petromyzon marinus genome reveals the early origin of several chemosensory receptor families in the vertebrate lineage

open access: yesBMC Evolutionary Biology, 2009
Background In gnathostomes, chemosensory receptors (CR) expressed in olfactory epithelia are encoded by evolutionarily dynamic gene families encoding odorant receptors (OR), trace amine-associated receptors (TAAR), V1Rs and V2Rs.
Zhang Ziping   +7 more
doaj   +1 more source

An update on anatomy and function of the teleost olfactory system [PDF]

open access: yesPeerJ, 2019
About half of all extant vertebrates are teleost fishes. Although our knowledge about anatomy and function of their olfactory systems still lags behind that of mammals, recent advances in cellular and molecular biology have provided us with a wealth of ...
Jesús Olivares, Oliver Schmachtenberg
doaj   +2 more sources

Optimizing Odorants for Olfactory Training Based on Olfactory Receptor–Ligand Pair Analysis

open access: yesThe Laryngoscope, Volume 136, Issue 1, Page 384-394, January 2026.
This study employs receptor–ligand interaction analysis and olfactory epithelium transcriptomics to optimize olfactory training (OT). A novel four‐odorant combination (galaxolide, eugenol acetate, [−]‐menthol, geranyl acetate) activates 83.9% of 385 human olfactory receptors (ORs), covering 69.9% of estimated OR expression—significantly outperforming ...
Hironobu Nishijima   +7 more
wiley   +1 more source

Longitudinal patterns of penile human papillomavirus detection among Ugandan men: A prospective sampling study

open access: yesInternational Journal of Cancer, Volume 157, Issue 12, Page 2455-2462, 15 December 2025.
What's New? Human papillomavirus (HPV) is one of the most common sexually transmitted infections among humans and is associated with cancers in both women and men. While HPV testing is often conducted in the context of cervical cancer screening, men are also susceptible to HPV‐related cancers, and they play an important role in transmitting the virus ...
Xinyi Feng   +11 more
wiley   +1 more source

Modified Chromenes as Precursors to TAAR Regulators [PDF]

open access: yes, 2011
200 million people worldwide are living with a thyroid disorder related to a hormonal imbalance. Symptoms of this imbalance include deviations from normal heart rates and metabolic rates.
Lehmann, Jonathan, Hart, Matthew
core  

The maximum-likelihood phylogeny of TAAR proteins from 24 gnathostome genomes.

open access: yes, 2016
All functional proteins in tetrapods, nine representative teleost proteins, and two elephant shark TAARs are included in the analysis. TAAR V as well as the lamprey TAAR-like sequences are used as the outgroup.
Federico G. Hoffmann (367043)   +3 more
core   +1 more source

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