Results 51 to 60 of about 139,444 (306)
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Knowledge transfer for innovativeness in family businesses
Serbian Journal of Management, 2021 Family businesses (FB) are important in the most of national economies. We explored whether successors’ innovativeness is positively associated with the transfer of the founders’ innovativeness through knowledge transfer and creation processes in a form ...
Marina Letonja, Mojca Duh, Zdenka Ženko
doaj +1 more source
Review of the Use of the Terms ‘Knowledge Transfer’ and ‘Knowledge Exchange’ [PDF]
, 2011 Knowledge Transfer is a topic taught on MBA courses across the world and recognised as a professional discipline (e.g. the Institute of Knowledge Transfer), an academic discipline (e.g.
Polkinghorne, Martyn
core
The Importance of Knowledge Transfer in Decision Making [PDF]
, 2014 This paper discusses the issues related to capturing and transferring knowledge in management consulting organization and proposes a framework to implement a knowledge transferring environment for intelligent working system. The proposed framework make
Akram, Anza
core +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Manufacturing Barriers to Biologics Competition and Innovation [PDF]
, 2016 As finding breakthrough small-molecule drugs gets harder, drug companies are increasingly turning to “large molecule” biologics. Although biologics represent many of the most promising new therapies for previously intractable diseases, they are extremely
Price, W. Nicholson, II, Rai, Arti K.
core +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
A Tacit-Knowledge-Based Requirements Elicitation Model Supporting COVID-19 Context
IEEE Access, 2022 Effective software requirements elicitation plays a vital role in the success or failure of a project. However, ambiguity in the requirement’s statements indicate the presence of a tacit knowledge, which ultimately act as a root cause of critical ...
Hamnah Anwar +3 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Tacit Knowledge Taxonomy and Transfer: Case-Based Research [PDF]
Journal of Behavioral and Applied Management, 2011 Tacit organizational knowledge is intangible, implicit, and profoundly attached to people (Spender, 2003). While highly complex, it is also a driving force of organizational performance, and its transfer crucial in capitalizing on existing resources (Cross & Baird, 2000).
openaire +1 more source