Results 121 to 130 of about 73,761 (306)

Tacrolimus 4‐hour monitoring in liver transplant patients is non‐inferior to trough monitoring: The randomized controlled FK04 trial

Clinical Transplantation, Volume 36, Issue 12, December 2022., 2022
Abstract Background After liver transplantation (LT), tacrolimus and ciclosporin treatment can lead to, partially concentration‐dependent, chronic kidney disease. Monitoring ciclosporin with two‐hour levels reduced overexposure and led to better renal function than trough‐monitoring (C0).
Bastian N. Ruijter, Maarten E. Tushuizen, Dirk J. A. R. Moes, Babs M. de Klerk, Bart van Hoek   +4 more
wiley   +1 more source

Management of Cutaneous Lesions in Brunsting–Perry Pemphigoid (Bpp): A Single‐Center Retrospective Cohort Study

JEADV Clinical Practice, EarlyView.
Shirley P. Parraga, Matthew L. Hrin, Sarah N. Rimmer, Joseph L. Jorizzo   +3 more
wiley   +1 more source

Proteome of Renal Tubuli and Serum Differentiate Pre‐Existing Type 2 Diabetes and Post‐Transplant Diabetes in Kidney Transplant Recipients

PROTEOMICS – Clinical Applications, EarlyView.
ABSTRACT Purpose Diabetes mellitus (DM) is a major cause of end‐stage kidney disease (ESKD), with kidney transplantation being the preferred treatment. However, post‐transplant diabetes mellitus (PTDM) increases mortality and graft loss. While PTDM and Type 2 diabetes mellitus (T2DM) share risk factors, their mechanisms differ, particularly in diabetic
Eleni Skandalou, Mariell Rivedal, Hans‐Peter Marti, Thea A. S. Halden, Trond Jenssen, Bjørn Egil Vikse, Anders Åsberg, Jessica Furriol   +7 more
wiley   +1 more source

Proteomic study on the lymphocytes from pregnant Wistar rat females treated with immunosuppressive regimen

Clinical and Translational Science, Volume 16, Issue 1, Page 118-127, January 2023., 2023
Abstract Kidney transplantation remains the therapeutic option for patients with end‐stage kidney disease. Current immunosuppressive regimens are efficient in combating acute kidney rejection. However, insights into chronic kidney allograft injury remains limited.
Bartosz Wojciuk, Aleksandra Bogucka, Paulina Czaplewska, Patrycja Okulewicz, Iwona Wojciechowska‐Koszko, Kazimierz Ciechanowski, Joanna Kabat‐Koperska   +6 more
wiley   +1 more source

Preparation of tacrolimus ophthalmic solution using cyclodextrins

مجله دانشگاه علوم پزشکی بیرجند, 2017
Background and Aim: Application of topical tacrolimus in Vernal Keratoconjunctivitis is considered as an alternative to steroids. Due to the low aqueous solubility of  the drug, preparing a solution of the drug has got particular importance.
Farzaneh Hajiahmadi, Akbar Derkhshan, Maliheh Nikandish, Bizhan Malaekeh-Nikouei   +3 more
doaj  

PBPK Modeling: Empowering Drug Development and Precision Dosing in China

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Physiologically based pharmacokinetic (PBPK) modeling, a cornerstone of model‐informed drug development and model‐informed precision dosing, simulates drug disposition in the human body by integrating physiological, biochemical, and physicochemical parameters.
Dongsheng Yang, Jian Li, Wen Yao Mak, Aole Zheng, Xiao Zhu, Qingfeng He, Yuzhu Wang, Xiaoqiang Xiang   +7 more
wiley   +1 more source

Effect of peritransplant FTY720 alone or in combination with post-transplant tacrolimus in a rat model of cardiac allotransplantation [PDF]

, 1998
Min Xu, Jacques Pirenne, Efstathios Antoniou, Simon C. Afford, Milbhor D’Silva, Paul McMaster   +5 more
openalex   +1 more source

Treatment strategy for systemic lupus erythematosus using belimumab as indicated by multi‐omics analysis

Rheumatology &Autoimmunity, EarlyView.
Recent multi‐omics studies have demonstrated that belimumab specifically targets naïve B cells and a subset of memory B cells. This observation is consistent with belimumab's established efficacy and safety profile. Abstract Belimumab is an antibody targeting the cytokine B‐cell activating factor (BAFF), which is crucial for B cell differentiation, and
Keishi Fujio, Toshiyuki Ushijima, Tatsuki Abe, Tomohisa Okamura, Sang‐Cheol Bae, Yumi Tsuchida   +5 more
wiley   +1 more source

RESCUE THERAPY WITH TACROLIMUS AFTER COMBINED KIDNEY/PANCREAS AND ISOLATED PANCREAS TRANSPLANTATION IN PATIENTS WITH SEVERE CYCLOSPORINE NEPHROTOXICITY1

, 1996
Sundaram Hariharan, Rino Munda, Tito Cavallo, A.M Demmy, Timothy J. Schroeder, J. Wesley Alexander, Matthew R. First   +6 more
openalex   +1 more source

Tacrolimus Enhances the Immunosuppressive Effect of Cyclophosphamide But Not That of Leflunomide or Mycophenolate mofetil in a Model of Discordant Liver Xenotransplantation [PDF]

, 1998
Toshio Miki, A.L Goller, A S Rao, X. Wang, W. Yin, A Tandin, John J. Fung, Thomas E. Starzl, L A Valdivia   +8 more
openalex   +1 more source