Results 131 to 140 of about 130,661 (316)

Comparing tacrolimus level monitoring in peripheral blood mononuclear cells and whole blood within one year after kidney transplantation: a single-center, prospective, observational study

Frontiers in Pharmacology
BackgroundTacrolimus, a key immunosuppressant for kidney transplant recipients, is traditionally monitored through whole-blood trough concentrations. However, this approach may not accurately reflect lymphocyte tacrolimus levels, limiting its predictive ...
Jia You, Jia You, Jia You, Rui Chen, Rui Chen, Yuhui Chai, Xue Wang, Wenmin Xie, Yunyun Yang, Kaile Zheng, Kaile Zheng, Kaile Zheng, Lizhi Chen, Zhuo Wang, Xuebin Wang, Xuebin Wang, Xuebin Wang   +16 more
doaj   +1 more source

Era of direct acting anti-viral agents for the treatment of hepatitis C. [PDF]

, 2018
Hepatitis C infection is universal and the most common indication of liver transplantation in the United States. The period of less effective interferon therapy with intolerable side effects has gone.
Ahmed, Monjur
core   +1 more source

Effect of oral itraconazole on the pharmacokinetics of tacrolimus in a hematopoietic stem cell transplant recipient with CYP3A5*3/*3 [PDF]

, 2010
Miho Nara, Naoto Takahashi, Masatomo Miura, H Saitoh, H.‐Matsuo Kagaya, Kenichi Sawada   +5 more
openalex   +1 more source

Drug–drug interaction between tacrolimus and caspofungin in Chinese kidney transplant patients with different genotypes

Therapeutic Advances in Drug Safety
Background: The effect of drug–drug interaction between tacrolimus and caspofungin on the pharmacokinetics of tacrolimus in different CYP3A5 genotypes has not been reported in previous studies.
Yundi Zhang, Bowen Shen, Yue Li, Huiying Zong, Xiaoming Zhang, Xiaohong Cao, Fengxi Liu, Yan Li   +7 more
doaj   +1 more source

In vitro assessment of the risk of ABCB1-mediated drug–drug interaction between rivaroxaban and tacrolimus in human embryonic kidney 293 recombinant cell lines

Research and Practice in Thrombosis and Haemostasis
Background: In lung transplant patients, direct oral anticoagulants are often taken in combination with immunosuppressive drugs such as tacrolimus. Since tacrolimus is a substrate and inhibitor of the efflux protein ABCB1, also transporting direct oral ...
Gwenaëlle Mahieu, Anne-Laure Sennesael, Lionel Pochet, Vincent Haufroid, Françoise Van Bambeke, Anne Spinewine, Laure Elens   +6 more
doaj   +1 more source

Randomised trialomania? The multicentre liver transplant trials of tacrolimus [PDF]

, 1995
Donner, A, Eliasziw, M, Fung, JJ, McMichael, JP, Meier, P, Starzl, TE, Stitt, L, Todo, S   +7 more
core   +1 more source

Assessment of tacrolimus intrapatient variability in stable adherent transplant recipients: Establishing baseline values [PDF]

, 2018
Abbie D. Leino, Eileen King, Wenlei Jiang, Alexander A. Vinks, Jost Klawitter, Uwe Christians, E. Steve Woodle, Rita R. Alloway, Jennifer Rohan   +8 more
openalex   +1 more source

Cumulative exposure to tacrolimus is associated with increased risk of malignancy for solid organ transplant recipients

International Journal of Cancer, EarlyView.
What's New? Long‐term immunosuppression in solid organ transplant recipients (SOTRs) is linked to increased cancer risk. Although this risk potentially increases with greater immunosuppressant exposure, the exact dose‐response pattern remains uncertain.
Sergio A. Acuna, Xun Zhao, Maggie Jones‐Carr, Graham Smith, Kyla Naylor, Bima J. Hasjim, Shiyi Chen, An‐Wen Chan, Nancy Baxter, S. Joseph Kim, Mamatha Bhat   +10 more
wiley   +1 more source

Pediatric liver transplantation in 808 consecutive children: 20-Years experience from a single center [PDF]

, 2002
Fung, JJ, Jain, A, Kashyap, R, Kosmach-Park, B, Mazariegos, G, Reyes, J, Starzl, TE   +6 more
core   +1 more source

Efficacy and safety of tacrolimus compared with cyclosporin A microemulsion in renal transplantation: 2 year follow-up results [PDF]

, 2005
Bernhard K. Krämer, G. Montagnino, Domingo del Castillo, Raimund Margreiter, H Sperschneider, Christoph J. Olbricht, Bernd Krüger, J. Ortuño, Hans Köhler, Ulrich Kunzendorf, Hans–Krister Stummvoll, Josep Tabernero, Ferdinand Mühlbacher, M. Rivero, Manuel Arias   +14 more
openalex   +1 more source