Opportunities and Challenges of Population Pharmacogenomics
ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou+3 more
wiley +1 more source
INTERACTION BETWEEN TACROLIMUS AND CHLORAMPHENICOL IN A RENAL TRANSPLANT RECIPIENT
Seth L. Schulman+4 more
openalex +1 more source
Outcome of tacrolimus conversion therapy for renal allograft rejection: 5-year follow-up [PDF]
Mark L. Jordan+9 more
openalex +1 more source
This study investigated the therapeutic equivalence of CT‐P39 (an omalizumab biosimilar) and EU‐approved reference omalizumab (ref‐OMA) in patients with chronic spontaneous urticaria. Therapeutic equivalence between CT‐P39 and ref‑OMA (300 mg) was demonstrated by the primary endpoint – confidence intervals of the treatment difference in mean change ...
Sarbjit S. Saini+16 more
wiley +1 more source
ORAL TACROLIMUS TREATMENT OF SEVERE COLITIS IN CHILDREN: LONG-TERM FOLLOWUP
Athos Bousvaros+11 more
openalex +1 more source
Optimizing Tacrolimus Dosing During Hospitalization After Kidney Transplantation: A Comparative Model Analysis. [PDF]
Mok S+5 more
europepmc +1 more source
Tacrolimus Ointment does not Affect Collagen Synthesis: Results of a Single-Center Randomized Trial
Sakari Reitamo+7 more
openalex +1 more source
Tacrolimus versus cyclosporin for immunosuppression in renal transplantation: meta-analysis of randomised trials [PDF]
Greg Knoll, Richard Bell
openalex +1 more source
Abstract Background Growing evidence indicates that paternal condition significantly influences pregnancy outcomes and offspring health. However, assessing the safety of paternal drug exposure via randomized controlled trials poses ethical challenges, and relevant clinical studies consume a lot of resources to evaluate only a few drugs.
Yanbin Zeng, Wanlong Lin, Wei Zhuang
wiley +1 more source
Robust UPLC-MS/MS Method With Acetonitrile for Precise Intracellular Quantification of Tacrolimus in PBMCs: A Step Toward Clinical Integration. [PDF]
Tanathitiphuwarat N+3 more
europepmc +1 more source