Results 171 to 180 of about 157,199 (404)

Genetically‐targeted control of the spinal cord and peripheral nervous system

Journal of Intelligent Medicine, EarlyView.
Application of genetically‐targeted stimulation for treating diseases or injuries outside the brain. Optogenetic and chemogenetic systems have been developed for dysfunction in the cochlea, spinal cord, dorsal root ganglia (DRGs), peripheral nerves, lower urinary tract, and enteric nervous system (ENS). Created with Biorender.com.
Anakaren Romero Lozano, Victoria Koptelova, Zoya Ahmad, Huiliang (Evan) Wang   +3 more
wiley   +1 more source

Marginal Structural Modeling of Representative Treatment Trajectories [PDF]

arXiv
Marginal structural models (MSMs) are widely used in observational studies to estimate the causal effect of time-varying treatments. Despite its popularity, limited attention has been paid to summarizing the treatment history in the outcome model, which proves particularly challenging when individuals' treatment trajectories exhibit complex patterns ...
arxiv  

Improved kidney function and one-year survival with transitioning from intravenous to enteral tacrolimus in lung transplant recipients

Transplantation Reports
Background: Acute kidney injury (AKI) is common after lung transplant and may increase risk of chronic kidney disease (CKD). Calcineurin inhibitors (CNIs) such as tacrolimus contribute to AKI risk.
Carrie Burt, Georgina Waldman, Linda Awdishu, Kamyar Afshar, Mark Mariski, Jade Kozuch, Gordon Yung, Eugene Golts, Ashley Feist   +8 more
doaj  

Update on the clinical utility of once-daily tacrolimus in the management of transplantation

Drug Design, Development and Therapy, 2014
Maria Aurora Posadas Salas, Titte R Srinivas Division of Nephrology and Hypertension, Department of Medicine, Medical University of South Carolina, Charleston, SC, USA Abstract: Adherence to immunosuppression and minimizing variability in drug exposure ...
Posadas Salas MA, Srinivas TR
doaj  

Tacrolimus treatment in women with repeated implantation failures

Reproductive Medicine and Biology
Background Tacrolimus is an immunosuppressive drug that works as a calcineurin inhibitor to improve the reproductive outcomes for women who have experienced multiple implantation failures (RIF) and show elevated type 1 helper T (Th1)/Th2 cell ratios ...
Koji Nakagawa, Rikikazu Sugiyama
doaj   +1 more source

Intestinal involvement in graft versus host disease in children: An overview by the ESPGHAN Gastroenterology Committee

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Graft versus host disease (GVHD) is a complication that frequently occurs after haematopoietic stem cell transplantation and concerns many children in paediatric haematology‐oncology and bone marrow transplantation departments. It can affect various organs, with the skin, gastrointestinal tract and liver being the most commonly involved.
Marina Vincent, Amit Assa, Osvaldo Borrelli, Matjaž Homan, Javier Martin‐de‐Carpi, Zrinjka Misak, Maria Giovanna Puoti, Isabelle Scheers, Sara Sila, Caterina Strisciuglio, Christos Tzivinikos, Jernej Dolinsek, Emmanuel Mas   +12 more
wiley   +1 more source

Have we hit the JAK‐pot? Success of selective JAK 1 inhibitor following failure of pan‐JAK inhibitor in refractory pediatric ulcerative colitis

JPGN Reports, EarlyView.
Abstract The treatment options available for pediatric ulcerative colitis (UC) are challenging due to few with Federal Drug Administration approval. Newer medications approved for adults include additional biologics with differing mechanisms of action and small molecule drugs, such as Janus kinase (JAK) inhibitors.
Jessica A. Black, Brad Pasternak
wiley   +1 more source

Management of Mild‐to‐Moderate Atopic Dermatitis With Topical Treatments by Dermatologists: A Questionnaire‐Based Study

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Atopic dermatitis (AD) is a chronic, immune‐mediated, inflammatory skin disorder affecting a heterogeneous population. Most patients with mild‐to‐moderate AD are treated with topical medication. Objectives To gain an understanding of the management of mild‐to‐moderate AD with topical treatments by examining the practices of ...
Lawrence F. Eichenfield, Linda F. Stein Gold, Adelaide A. Hebert, Lyn Guenther, Yuliya Valdman‐Grinshpoun, Dan Ben‐Amitai, Roni P. Dodiuk‐Gad, Michael J. Cork, Valeria Aoki, Chia‐Yu Chu, Jianzhong Zhang, Lin Ma, Hidehisa Saeki, Paula C. Luna, Mark Jean‐Aan Koh   +14 more
wiley   +1 more source

Pancreatic transplantation at the University of Pittsburgh. [PDF]

, 2004
Campath-1H preconditioning with tacrolimus monotherapy is an effective immunosuppressive regimen for pancreas transplantation, with acceptable patient and graft survival rates early after transplantation.
Abu-Elmagd, K, Basu, A, Bond, G, Khan, A, Marcos, A, Mazariegos, G, Reyes, J, Shapiro, R, Sindhi, R, Starzl, TE, Tan, HP, Thai, NL, Tom, K   +12 more
core  

Tacrolimus versus cyclosporin for immunosuppression in renal transplantation: meta-analysis of randomised trials [PDF]

, 1999
Greg Knoll, Richard Bell
openalex   +1 more source