Results 81 to 90 of about 73,761 (306)

The use of steroids in adult epilepsy: A systematic review

Epilepsia Open, EarlyView.
Abstract Objective The objective of this study is to systematically review the clinical studies investigating the use of steroids in adult epilepsy. Methods This systematic review utilized Preferred Reporting Items for Systematic Review and Meta‐analysis Protocols (PRISMA‐P) to examine literature on the use of steroids in adult epilepsy.
Ruth Walsh, Colin P. Doherty, Elisabeth Doran   +2 more
wiley   +1 more source

A randomized phase II study to evaluate tacrolimus in combination with sirolimus or methotrexate after allogeneic hematopoietic cell transplantation

Haematologica, 2012
Background There is evidence suggesting that sirolimus, in combination with tacrolimus, is active in the prevention of graft-versus-host disease. Sirolimus-based immune suppression may suppress alloreactive T cells, while sparing the survival and ...
Joseph Pidala, Jongphil Kim, Heather Jim, Mohamed A. Kharfan-Dabaja, Taiga Nishihori, Hugo F. Fernandez, Marcie Tomblyn, Lia Perez, Janelle Perkins, Mian Xu, William E. Janssen, Anandaraman Veerapathran, Brian C. Betts, Frederick L. Locke, Ernesto Ayala, Teresa Field, Leonel Ochoa, Melissa Alsina, Claudio Anasetti   +18 more
doaj   +1 more source

Three cases of atypical Rasmussen's encephalitis with delayed‐onset seizures

Epilepsia Open, EarlyView.
Abstract We retrospectively analyzed the clinical characteristics of three ARE cases with delayed‐onset seizures treated at Peking University First Hospital and Sanbo Brain Hospital from May 2021 to January 2023. We also reviewed previously reported atypical cases of Rasmussen's encephalitis (RE) in the literature, summarizing onset symptoms, seizure ...
Hongru Guo, Pan Gong, Guojing Yu, Chongyang Tang, Guoming Luan, Qingzhu Liu, Lixin Cai, Taoyun Ji   +7 more
wiley   +1 more source

Improving Production of Tacrolimus In Streptomyces Tacrolimicus (ATCC 55098) Through Development of Novel Mutant by Dual Mutagenesis

Brazilian Archives of Biology and Technology, 2017
Tacrolimus is a polyketide macrolide produced by Streptomyces species which is widely used as anti-fibrotic agent and potent immunosuppressant. In this article dual mutagenesis approach using mutagens (NTG+EMS+UV) was used to develop a mutant strain of ...
Bhanu P Singh, Punit Kumar, Shafiul Haque, Arshad Jawed, Kashyap Kumar Dubey   +4 more
doaj   +1 more source

An Elastomeric Polymer Matrix, PEUU-Tac, Delivers Bioactive Tacrolimus Transdurally to the CNS in Rat

EBioMedicine, 2017
Central nervous system (CNS) neurons fail to regrow injured axons, often resulting in permanently lost neurologic function. Tacrolimus is an FDA-approved immunosuppressive drug with known neuroprotective and neuroregenerative properties in the CNS ...
Yolandi van der Merwe, Anne E. Faust, Ian Conner, Xinzhu Gu, Firuz Feturi, Wenchen Zhao, Bianca Leonard, Souvik Roy, Vijay S. Gorantla, Raman Venkataramanan, Kia M. Washington, William R. Wagner, Michael B. Steketee   +12 more
doaj   +1 more source

Impact of genetic polymorphisms on tacrolimus concentrations and intra-individual variability in recipients of heart transplants during the early post-heart transplantation period [PDF]

arXiv
This study aimed to investigate the effects of genetic polymorphisms on tacrolimus blood levels and intra-individual variability in recipients of heart transplants during the early post-transplantation period. Demographic information, concomitant medications, daily tacrolimus dose, trough concentration, and physiological and biochemical information of ...
arxiv  

Measurement of blood concentrations of FK506 (tacrolimus) and its metabolites in seven liver graft patients after the first dose by h.p.l.c.‐MS and microparticle enzyme immunoassay (MEIA). [PDF]

, 1994
AK Gonschior, Uwe Christians, Felix Braun, M. Winkler, A Linck, J. Baumann, K.‐Fr. Sewing   +6 more
openalex   +1 more source

Safety of a trial of labor after cesarean in kidney and liver transplant recipients: A multicenter cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To evaluate the trends, safety, and feasibility of a trial of labor after cesarean (TOLAC) among kidney and liver transplant recipients. Methods This was a retrospective cohort study using the Transplant Pregnancy Registry International.
Anjali Walia, Ophelia Yin, Lisa A. Coscia, Serban Constantinescu, Monika Sarkar, Michael J. Moritz, Yalda Afshar, Roxanna A. Irani   +7 more
wiley   +1 more source

Drug-drug interaction between diltiazem and tacrolimus in relation to CYP3A5 genotype status in Chinese pediatric patients with nephrotic range proteinuria: a retrospective study

Frontiers in Pharmacology
BackgroundTacrolimus is widely used to treat pediatric nephrotic range proteinuria (NRP). Diltiazem, a CYP3A4/5 inhibitor, is often administered with tacrolimus, affecting its pharmacokinetic profile. The impact of this combination on tacrolimus exposure,
Qiaoling Yang, Qiaoling Yang, Yan Wang, Yan Wang, Xuebin Wang, Ping Wang, Boyu Tan, Yijun Li, Huajun Sun, Wenyan Huang, Hongxia Liu   +10 more
doaj   +1 more source

Tacrolimus (FK 506)--a new therapeutic agent for severe recalcitrant psoriasis [PDF]

, 1992
B V Jegasothy
openalex   +1 more source