Results 61 to 70 of about 34,240 (280)

Modelling and prototyping of a microfluidic cartridge for extracting immune cells from small volume blood samples

Current Directions in Biomedical Engineering, 2020
Within the human blood immune cells assume specific functions to modulate and control the human immune response. Consequently, they are used for the diagnosis and treatment of autoimmune and hematologic diseases.
Behrens Stephan, Sonntag Frank, Schmieder Florian   +2 more
doaj   +1 more source

Lack of Immediate Effects on Excitation and Interhemispheric Inhibition of the Human Motor Cortex [PDF]

, 2016
Transcranial alternating current stimulation (tACS) is a form of noninvasive brain stimulation and is capable of influencing brain oscillations and cortical networks.
Gundlach, Christopher, Hoff, Maike, Kaminski, Elisabeth, Ragert, Patrick, Rjosk, Viola, Sehm, Bernhard, Villringer, Arno   +6 more
core   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

The Effects of 10 Hz Transcranial Alternating Current Stimulation on Audiovisual Task Switching

Frontiers in Neuroscience, 2018
Neural oscillations in the alpha band (7–13 Hz) are commonly associated with disengagement of visual attention. However, recent studies have also associated alpha with processes of attentional control and stability.
Michael S. Clayton, Nick Yeung, Roi Cohen Kadosh   +2 more
doaj   +1 more source

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

Advanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen, Lian Lou, Xuan Zhang, Lin Yan, Qi Zhang, Wen Shi, Jie Ding, Xu Lin, Rong Jiang, Shuo Liu, Thida Sok, Pengli Wang, Yun Mou, Jie Han, Shenjiang Hu, Xiaogang Guo, Jian Yang   +16 more
wiley   +1 more source

Frequency-specific modulation of motor cortical excitability by transcranial alternating current stimulation

Journal of NeuroEngineering and Rehabilitation
Background Transcranial alternating current stimulation (tACS) is a non-invasive technique that modulates neural oscillations, yet its specific effects on cortical excitability are not well-understood.
Lei Tingting, Chen Lilin, Wang Chuangjia, Si Jiamen, Zhang Shuxian, Ai Yinan, Liu Hanjun, Zheng Haiqing   +7 more
doaj   +1 more source

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source

Conformationally Driven Dual Fluorescence Properties of Higher Heteroacenes With Periodically Incorporated Boron Atoms

Angewandte Chemie, EarlyView.
We herein report the synthesis of a new heteroheptacene derivative with periodically incorporated six boron atoms. This compound exhibits dual fluorescence attributed to two interconvertible conformers that result from a delicate balance between the extended π‐system and the steric demand of bulky aryl groups attached to the boron centers.
Takeshi Yokochi, Hiromichi Yokoyama, Tetsuyoshi Tsukada, Hayato Sakai, Taku Hasobe, Takanori Fukushima, Yoshiaki Shoji   +6 more
wiley   +2 more sources

Behavioral entrainment to rhythmic auditory stimulation can be modulated by tACS depending on the electrical stimulation field properties

eLife
Synchronization between auditory stimuli and brain rhythms is beneficial for perception. In principle, auditory perception could be improved by facilitating neural entrainment to sounds via brain stimulation. However, high inter-individual variability of
Yuranny Cabral-Calderin, Daniela van Hinsberg, Axel Thielscher, Molly J Henry   +3 more
doaj   +1 more source

A conclusive experiment to throw more light on "light"

, 2004
We describe a new realization of Ghose, Home, Agarwal experiment on wave particle duality of light where some limitations of the former experiment, realized by Mizobuchi and Ohtake, are overcome.
Brida, G., Genovese, M., Gramegna, M., Predazzi, E.   +3 more
core   +2 more sources