Results 91 to 100 of about 2,066 (198)
A quantitative dissection of the DNA‐binding properties of pathogenic GATA1 mutants
The FEBS Journal, EarlyView.Transcription factor activity is influenced by cell context, accessibility of target sequences, and co‐factor recruitment. Quantitatively characterizing the consequences of individual mutations in the transcription factors or their target sequences remains technically challenging. Zambo et al. use mutant GATA1‐ATP2B4 binding to illustrate an innovation
Kaoru Takasaki
wiley +1 more source
TAD boundaries and gene activity are uncoupled
eLifeTopologically associating domains (TADs) are prominent features of genome organization. A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs.
Faisal Almansour +6 more
doaj +1 more source
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Introduction Investigator‐led research and quality improvement initiatives have led to important improvements in the diagnostic assessment of platelet function disorders (PFD). Methods Personal reflections were used to summarize our contributions to knowledge on PFD diagnostic assessment, pathogenesis, and bleeding risks.
Catherine P. M. Hayward
wiley +1 more source
Scientific ReportsTemporary anchorage devices (TADs) provide maximum anchorage in orthodontic therapy. Surgical guides can be used to accurately achieve pre-planned TAD positions.
Lea Hoffmann +7 more
doaj +1 more source
A ‘TAD’ easier to calculate! [PDF]
The Annals of The Royal College of Surgeons of England, 2014 openaire +2 more sources
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Introduction RUNX1 is a commonly mutated transcriptional regulator of hematopoiesis in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Mutated RUNX1 (mRUNX1) may associate with cross‐lineage immunophenotypic aberrancy, presenting potential complications for blast lineage assignment at diagnosis. Methods Clinical and laboratory
Yi Han Xia, Eric McGinnis
wiley +1 more source
Palamism Does Not Disfigure the Gospel: A Reply to Thomas Weinandy
International Journal of Systematic Theology, EarlyView.Abstract In a 2024 article in the IJST, Fr. Thomas Weinandy argues that the theological system of Gregory Palamas is in grave error, especially with respect to its commitment to an objective ontological distinction between God's essence and His energies. In his concluding paragraph Fr.
Travis Dumsday
wiley +1 more source
Immunology, EarlyView.Distribution of studies on HIV‐1 Gag cytotoxic T‐lymphocyte epitopes in the southern African region showing that the majority of studies (58.44%) were conducted in South Africa, followed by Botswana (15.58%), Zambia (10.39%), Malawi (7.79%), Zimbabwe (6.49%), and Angola (1.30%).
Tumelo L. Fortuin +4 more
wiley +1 more source