Results 81 to 90 of about 50,398 (264)

MYLK c.4079G>A, p.(Gly1360Asp) Variant Associated With Hereditary Thoracic Aortic Diseases and Early Onset Aortic Dissection

Annals of Human Genetics, EarlyView.
ABSTRACT Aims Thoracic aortic aneurysms and dissections are major causes of sudden cardiovascular death. We aimed to evaluate the clinical significance of the MYLK c.4079G>A, p.(Gly1360Asp) variant in Finnish families with heritable thoracic aortic disease (HTAD) and to assess evidence for a potential founder effect.
Minja Virtanen, Sini Keskinen, Rikhard Björn, Minna Paavola, Pia Pohjola, Marja Hietala, Maria K. Haanpää, Markus Malmberg, Elisa Rahikkala   +8 more
wiley   +1 more source

Clinical Relevance of the SOUND and INSEMA Trials in Women With Early Breast Cancer in Australia and New Zealand

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Axillary surgery in breast cancer has undergone progressive de‐escalation. The recent Sentinel Node versus Observation after Axillary Ultrasound (SOUND) and Intergroup Sentinel Mamma (INSEMA) trials have demonstrated that sentinel lymph node biopsy may be safely omitted in selected patients. This study aimed to evaluate the clinical
Matea Dominkovic, Kerry Hitos, Wei Wang, T. Michael Hughes, James French, Nicholas Ngui   +5 more
wiley   +1 more source

#dametuits: Programa de formación y comunicación corporativa gamificada

Obra Digital, 2014
#dametuits fue un programa puesto en marcha en el Centro Universitario de Tecnología y Arte Digital (U-tad) que tenía como objetivo el cambio de modelo comunicacional de la institución por medio del fomento de la participación formada y optimizada de los
Carlos González Tardón, Rebeca Amieva de la Vega   +1 more
doaj   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

The effectiveness of low‐intensity mental health interventions for children and young people in England: a presentation and analysis of synthesised outcomes

Child and Adolescent Mental Health, EarlyView.
Background Despite rapid national implementation of the new low‐intensity (LI) children and young people's (CYP) mental health (MH) workforce, outcomes have not been synthesised at scale. Methods This paper presents retrospective, uncontrolled routine outcome data collected between July 2017 and May 2025 from LI services across several regions of ...
Susanna Payne, Deepa Mavji, Caroline Stokes, Jessica Richardson, Jonathan Parker, Catherine Gallop, Hollie Gay, Katy Snitter, Elizabeth Deacon, Lili Ly, Vicki Curry, Markku Wood, Tyler Lewis, Cara Miller, Nicola Abraham, Elizabeth Turnbull, Melika Janbakhsh, Nicholas Smith, Helen Barker, Sadie Williams, Laura Bowyer, Kellie Jacques, Mike Turnbull, Jessica Collins, Alisa Kurina, Natalie Fabian, Anne Matthews, Barbara Evetts, Jeevan Kang, Alison Wheeler, Peter Fonagy   +30 more
wiley   +1 more source

Tad Lauritzen Wright

, 2019
In his work, Tad Lauritzen Wright is interested in generating an impromptu reaction to an idea, thought, or experience. He has always been attracted to art work that comes from discounted sources.
Wright, Tad Lauritzen
core   +1 more source

Tad Fujita, interviewed by Sandra Taylor on October 28, 1987

, 1987
Typescript (40 pages), the transcript of an interview by Sandra C. Taylor with Tad Fujita, a Japanese-American living in Berkeley, California. Interview took place on October 28, 1987, on behalf of the American West Center at the University of ...
Fujita, Tad
core  

TOP1MT rs2293925 is an enhancer‐active regulatory SNP that shapes mitochondrial R‐loop dynamics

The FEBS Journal, EarlyView.
This study shows how a common genetic variant of mitochondrial topoisomerase 1 (TOP1MT rs2293925) can influence mitochondrial gene regulation, DNA topology, and formation of noncanonical nucleic acid structures such as R‐loops. By linking this enhancer‐active variant to mitochondrial nucleic acid stress in cellular contexts relevant to amyotrophic ...
Dóra Varga, Zsolt Ráduly, Beáta Boros‐Oláh, Éva Nagy, Zsolt Karányi, László Halász, Bálint László Bálint, György Vámosi, Emese Tóth, Péter Bai, Serena Santangelo, Patrizia Bossolasco, Antonia Ratti, Vincent Géli, Yves Pommier, Lóránt Székvölgyi   +15 more
wiley   +1 more source

UbiB proteins mediate an ATP‐dependent decarboxylation step in bacterial ubiquinone biosynthesis

The FEBS Journal, EarlyView.
UbiB proteins are atypical protein kinase‐like enzymes essential for ubiquinone biosynthesis. Here, we demonstrate that bacterial UbiB proteins catalyze the O2‐dependent decarboxylation of ubiquinone precursors, a process linked to their ATPase activity.
Katayoun Kazemzadeh, Bruno Faivre, Sophie‐Carole Chobert, Martial Rey, Sophie S. Abby, Julie Michaud, Tuan‐Anh Dinh, Alexandre Chilin, Olivier Lerouxel, Marc Fontecave, Fabien Pierrel, Murielle Lombard, Ludovic Pelosi   +12 more
wiley   +1 more source

El Diluvio Digital. Las preguntas esenciales de las humanidades en la sociedad Red.

Arte y Sociedad, 2019
Nuestra relación con el medio social está condicionada por flujos de información en los que las tecnologías digitales transforman cualquier aproximación y comprensión de los fenómenos culturales.
Jaime Repollés Llauradó
doaj