Results 101 to 110 of about 2,066 (198)

Calpain‐2‐Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection

open access: yesAdvanced Science
Thoracic aortic dissection (TAD) is a life‐threatening condition with high mortality rates. Recent research suggests a potential link between early‐stage TAD and endothelial barrier dysfunction, although the underlying mechanisms remain unclear.
Xiaomei Teng   +10 more
doaj   +1 more source

In situ architecture of the Tad pilus machine in Caulobacter crescentus

open access: yesmBio
The tight adherence (Tad) pilus is a broadly distributed and evolutionarily distinct subclass of type IV pili that mediate cell adhesion, biofilm formation, predation, and surface sensing in many bacteria, including Caulobacter crescentus, Myxococcus ...
James Iarocci   +8 more
doaj   +1 more source

Role of the tomato MARS1/ROUGH gene encoding a LYSINE‐SPECIFIC HISTONE DEMETHYLASE 1 in adventitious root and fruit skin formation

open access: yesJournal of Integrative Plant Biology, EarlyView.
The tomato mars1/rough mutant displays enhanced root regeneration and rough fruits due to ectopic cell proliferation. The causal gene encodes a lysine‐specific histone demethylase that normally maintains gene silencing. Its loss alters histone methylation, upregulating several genes, including those B‐type cyclins involved in tissue‐specific cellular ...
Eduardo Larriba   +14 more
wiley   +1 more source

Long‐Term Associations Between Energy Expenditure and CGM‐Derived Metrics in Adults With Type 1 Diabetes: A Retrospective Analysis of the Syntactiq Cockpit Database

open access: yes
Diabetes, Obesity and Metabolism, EarlyView.
Katharina Bünzel   +11 more
wiley   +1 more source

High‐quality genome of elite peanut cultivar ZH05 reveals subgenome asymmetry, pan‐genome diversity, and breeding insights

open access: yesJournal of Integrative Plant Biology, EarlyView.
A high‐quality reference genome for the elite peanut cultivar Zhonghua No. 5 revealed differing evolutionary paths between the two peanut subgenomes. SubA has higher overall gene expression and more open chromatin, whereas SubB has stronger structural organization, higher DNA methylation, and greater adaptive diversity associated with peanut evolution ...
Taihua Yang   +19 more
wiley   +1 more source

The 3D genome of Gigaspora margarita unveils stable chromatin and nucleolar organization and symbiont‐dependent genome dynamics

open access: yesNew Phytologist, EarlyView.
Summary Arbuscular mycorrhizal fungi (AMF) are widespread plant symbionts that enhance nutrient acquisition and influence ecosystem productivity. Previous chromosome‐level assemblies of the model species Rhizophagus irregularis revealed a two‐compartment genome architecture (active A and repressed B chromatin compartments), yet its conservation across ...
Ken Mugambi   +10 more
wiley   +1 more source

Fibroblast Activation Protein Promotes Thoracic Aortic Dissection via PLAUR/ITGB1‐Mediated Pro‐inflammatory Macrophage Polarization

open access: yesAdvanced Science
Background: Thoracic aortic dissection (TAD) is a lethal vascular emergency lacking targeted therapies. Fibroblast activation protein (FAP), a protease implicated in tissue remodeling, exhibits unknown roles in TAD pathogenesis.
Hongqiao Zhu   +7 more
doaj   +1 more source

Comparative Evaluation of Treatment Effectiveness in Skeletal Class III Malocclusion: Surgery‐First Approach Using Clear Aligners Versus Fixed Appliances

open access: yesOrthodontics &Craniofacial Research, EarlyView.
ABSTRACT Objective This study aimed to assess treatment outcomes, identify predictors of relapse in skeletal Class III patients treated with the surgery‐first approach (SFA), comparing fixed appliances (FA) with invisalign clear aligners (CA). Materials and Methods Forty adult patients treated with bimaxillary surgery and SFA were retrospectively ...
Yang Zhou   +3 more
wiley   +1 more source

Effects Produced by Fixed Functional Appliances With and Without Skeletal Anchorage for the Treatment of Class II Malocclusion in the Growing Patient: A Review of Systematic Reviews

open access: yesOrthodontics &Craniofacial Research, EarlyView.
ABSTRACT To summarise the scientific evidence from systematic reviews on the differences between fixed functional appliances (FFA) with and without skeletal anchorage for the treatment of Class II malocclusion in growing patients. A systematic search on six major databases was performed.
Valentina Rutili   +4 more
wiley   +1 more source

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