Multiple genetic associations with Irish wolfhound dilated cardiomyopathy [PDF]
, 2016 Cardiac disease is a leading cause of morbidity and mortality in dogs and humans, with dilated cardiomyopathy being a large contributor to this. The Irish Wolfhound (IWH) is one of the most commonly affected breeds and one of the few breeds with genetic ...
Brownlie, Serena +7 more
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Cardiolipin biosynthesis and remodeling enzymes are altered during development of heart failure
Journal of Lipid Research, 2009 Cardiolipin (CL) is responsible for modulation of activities of various enzymes involved in oxidative phosphorylation. Although energy production decreases in heart failure (HF), regulation of cardiolipin during HF development is unknown.
Harjot K. Saini-Chohan +8 more
doaj +1 more source
Newsletter, 2011-09, no. 56 [PDF]
, 2011 The newsletter contains both association business and material of interest to midwives and related health care workers.The Association's name has changed several times based on the newsletter: from January 1992 - January 1997 it was The Alliance of Nurse-
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A genetic variant in large tumor suppressor kinase 2 of Hippo signaling pathway contributes to prognosis of hepatocellular carcinoma [PDF]
, 2016 published_or_final_versio
Chen, J +9 more
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Journal of Inborn Errors of Metabolism and Screening, 2015 Mutations in the tafazzin ( TAZ ) gene on chromosome Xq28 are responsible for the Barth syndrome (BTHS) phenotype resulting in a loss of function in the protein tafazzin involved in the transacylation of cardiolipin, an essential mitochondrial ...
Minal Borkar PhD +6 more
doaj +1 more source
Relations structure/fonction de la dynamine mitochondriale Msp1 : étude de ses relations avec la membrane interne et de ses activités biochimiques [PDF]
, 2011 La dynamique mitochondriale est définie comme un équilibre entre des forces antagonistes de fusion et de fission des membranes qui modulent la morphologie des mitochondries et jouent un rôle majeur dans la régulation des fonctions de l'organelle.
Diot, Alan
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G-Protein coupled receptor signalling in pluripotent stem cell-derived cardiovascular cells: Implications for disease modelling [PDF]
, 2015 Human pluripotent stem cell derivatives show promise as an in vitro platform to study a range of human cardiovascular diseases. A better understanding of the biology of stem cells and their cardiovascular derivatives will help to understand the strengths
Dolatshad, NF +4 more
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Genomic insights into cardiomyopathies: a comparative cross-species review [PDF]
, 2017 n the global human population, the leading cause of non-communicable death is cardiovascular disease. It is predicted that by 2030, deaths attributable to cardiovascular disease will have risen to over 20 million per year.
Beffagna +21 more
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Barth syndrome: mechanisms and management
The Application of Clinical Genetics, 2019 Josef FinstererKrankenanstalt Rudolfstiftung, Messerli Institute, Vienna, AustriaObjectives: Barth syndrome is an ultra-rare, infantile-onset, X-linked recessive mitochondrial disorder, primarily affecting males, due to variants in TAZ encoding for the ...
Finsterer J
doaj
Balkan Journal of Medical Genetics, 2016 Barth syndrome (BTHS) is a rare X-linked disease characterized by dilated cardiomyopathy, proximal skeletal myopathy and cyclic neutropenia. It is caused by various mutations in the tafazzin (TAZ) gene located on Xq28 that results in remodeling of ...
Bakšienė M +5 more
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