Results 101 to 110 of about 2,943 (200)
Effect of mild medical hypothermia on in vitro growth of Plasmodium falciparum and the activity of anti-malarial drugs [PDF]
, 2016 BACKGROUND: Cerebral malaria remains a medical emergency with high mortality. Hypo-perfusion due to obstructed blood vessels in the brain is thought to play a key role in the pathophysiology of cerebral malaria leading to neurological impairment, long ...
Felix Lötsch +5 more
core +1 more source
Shrinking the Malaria Map: A Prospectus on Malaria Elimination [PDF]
, 2009 \ud Thirty-nine countries across the world are making progress toward malaria elimination. Some are committed to nationwide elimination, while others are pursuing spatially progressive elimination within their borders.
Feachem, Richard G.A. +2 more
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Infection and Drug Resistance, 2019 Aurore B Hounkpatin,1–3,* Andrea Kreidenweiss,1,2,* Jana Held1–3 1Institute of Tropical Medicine, Eberhard Karls University Tübingen, Tübingen, Germany; 2German Centre for Infection Research, Partner Site Tübingen, Tü ...
Hounkpatin AB, Kreidenweiss A, Held J
doaj
Pharmacological considerations in the design of anti-malarial drug combination therapies - is matching half-lives enough? [PDF]
, 2014 Anti-malarial drugs are now mainly deployed as combination therapy (CT), primarily as a mechanism to prevent or slow the spread of resistance. This strategy is justified by mathematical arguments that generally assume that drug 'resistance' is a binary ...
Hodel, Eva Maria
core +1 more source
Epidemiología y tratamiento de Plasmodium vivax = The epidemiology and treatment of Plasmodium vivax [PDF]
, 2014 [spa] La carga de enfermedad y las muertes relacionadas con la malaria han disminuido a nivel global, principalmente gracias a las mejoras en la implementación de las intervenciones para prevenir y tratar la malaria, y en particular al uso de las ...
Betuela, Inoni
core +1 more source
Epidemiologie und Behandlung der importierten Malaria tropica [PDF]
, 2018 An der Malaria erkranken weltweit ca. 212 Millionen Menschen pro Jahr und ca. 430.000 Todesfälle an Malaria werden pro Jahr registriert. Die Malaria tropica wird durch Reisende und Migranten jedoch auch häufig nach Europa importiert.
Zoller, Thomas
core +1 more source
Recent advances, challenges and updates on the development of therapeutics for malaria
EXCLI Journal : Experimental and Clinical SciencesMalaria has developed as a serious worldwide health issue as a result of the introduction of resistant Plasmodium species strains. Because of the common chemo resistance to most of the existing drugs on the market, it poses a severe health problem and ...
Rimmy Nandal +10 more
doaj +1 more source
eLifeIn our recent paper on the clinical pharmacology of tafenoquine (Watson et al., 2022), we used all available individual patient pharmacometric data from the tafenoquine pre-registration clinical efficacy trials to characterise the determinants of anti ...
James A Watson +12 more
doaj +1 more source
The challenges of malaria elimination in the Asia–Pacific region
Medical Journal of Australia, Volume 221, Issue 4, Page 182-185, August 2024.
Freya JI Fowkes +5 more
wiley +1 more source
eLifeA single 300 mg dose of tafenoquine, in combination with chloroquine, is currently approved in several countries for the radical cure (prevention of relapse) of Plasmodium vivax malaria in patients aged ≥16 years.
Raman Sharma +10 more
doaj +1 more source