TAFRO Syndrome: Guidance for Managing Patients Presenting Thrombocytopenia, Anasarca, Fever, Reticulin Fibrosis, Renal Insufficiency, and Organomegaly [PDF]
TAFRO syndrome is an inflammatory disorder of unknown etiology characterized by thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly. Despite great advancements in research on the TAFRO syndrome in the last decade,
Katsuhiro Miura +15 more
doaj +2 more sources
Pathophysiology, Treatment, and Prognosis of Thrombocytopenia, Anasarca, Fever, Reticulin Fibrosis/Renal Failure, and Organomegaly (TAFRO) Syndrome: A Review [PDF]
TAFRO syndrome, first reported in 2010, is a systemic inflammatory disease with a rapid onset and potentially fatal course if not treated promptly and appropriately.
Takuya Kakutani +2 more
doaj +2 more sources
Primary Sjögren’s Syndrome Accompanied by Clinical Features of TAFRO Syndrome [PDF]
Sjögren’s syndrome (SS) is associated with not only sicca symptoms but also various symptoms caused by extraglandular manifestation. The pathophysiology and comorbidities of TAFRO syndrome (thrombocytopenia, anasarca, fever, reticulin fibrosis, and ...
Eiji Suzuki +4 more
doaj +4 more sources
TAFRO syndrome is associated with anti-SSA/Ro60 antibodies, in contrast to idiopathic castleman disease [PDF]
TAFRO syndrome is an acute systemic inflammatory disease characterized by thrombocytopenia, anasarca, fever, reticulin fibrosis/renal dysfunction, and organomegaly.
Mirei Shirakashi +9 more
doaj +2 more sources
TAFRO syndrome: New subtype of idiopathic multicentric Castleman disease [PDF]
Castleman disease (CD) describes a group of three rare and poorly understood lymphoproliferative disorders that have heterogeneous clinical symptoms and common lymph node histopathological features.
David C Fajgenbaum +3 more
core +5 more sources
Biomarkers and Signaling Pathways Implicated in the Pathogenesis of Idiopathic Multicentric Castleman Disease/Thrombocytopenia, Anasarca, Fever, Reticulin Fibrosis, Renal Insufficiency, and Organomegaly (TAFRO) Syndrome [PDF]
Idiopathic multicentric Castleman disease (iMCD) and TAFRO syndrome present a variety of symptoms thought to be caused by excessive inflammatory cytokines and chemokines, but the underlying mechanisms are unknown.
Remi Sumiyoshi +2 more
doaj +2 more sources
Severe coronavirus disease 2019 in a patient with TAFRO syndrome: A case report [PDF]
Background: TAFRO syndrome, a subtype of idiopathic multicentric Castleman disease, is an acute or subacute systemic inflammatory disease that causes fever, generalized oedema (pleural effusion or ascites), and thrombocytopenia and is associated with ...
Kengo Oshima +4 more
doaj +2 more sources
Multicentric Castleman disease presenting with orbital involvement progressing to TAFRO syndrome: a case report [PDF]
Background Castleman Disease (CD) can be unicentric or multicentric, with the ocular involvement rare; notably, the aggressive TAFRO syndrome (TS) is a subtype of idiopathic multicentric CD (iMCD). Ocular involvement in CD is rare, and to date, there are
Yuanfeng Wei +7 more
doaj +2 more sources
Stepwise Treatment for TAFRO Syndrome. [PDF]
TAFRO syndrome, a rapidly progressive and fatal disease, is rare, and its etiology remains unknown. It is characterized by thrombocytopenia, anasarca (edema, pleural effusion, and ascites), fever, reticulin fibrosis (or renal insufficiency), and organomegaly with Castleman disease (CD)-like histological features in the lymph nodes.
Ide M, Yokoyama T, Ishikawa M, Kojima K.
europepmc +3 more sources
Radiological Imaging Findings of Adrenal Abnormalities in TAFRO Syndrome: A Systematic Review [PDF]
This systematic review article aims to investigate the clinical and radiological imaging characteristics of adrenal abnormalities in patients with thrombocytopenia, anasarca, fever, reticulin fibrosis, renal dysfunction, and organomegaly (TAFRO) syndrome.
Ryo Kurokawa +6 more
doaj +2 more sources

