Results 51 to 60 of about 373,907 (280)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

The Overlap between the Descriptors of the Library Articles in LISTA Database and the Tags Assigned to the Same Articles in Folksonomy of Citeulike [PDF]

بازیابی دانش و نظام‌های معنایی, 2016
In this study, the amount of overlap between the descriptors of the library articles in LISTA database, and the tags assigned to the same articles inFolksonomy ofCiteulikewill be studied.
Masoumeh Mohammadpour, Esmat Momeni, Mehdi Alipour Hafezi   +2 more
doaj   +1 more source

Assignment of tracks from tagged Atlantic bluefin tuna Thunnus thynnus to potential stocks using behavioural differences and habitat partitioning

Frontiers in Marine Science, 2023
IntroductionAtlantic bluefin tuna (ABT) are large, migratory pelagic predators of high economic importance. ABT are currently managed as two independent stocks assigned to discrete spawning areas (Gulf of Mexico, and Mediterranean); however, stock ...
Simon Dedman, Simon Dedman, Emilius A. Aalto, Michael J. W. Stokesbury, Robert J. Schallert, Michael R. Castleton, Barbara A. Block   +6 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Effects of artificial light at night on the mobility of the sea urchin Paracentrotus lividus

Marine and Fishery Sciences, 2023
Light pollution poses a significant global threat to biodiversity, driven by the increasing coastal urbanization and the resulting growth of artificial light at night (ALAN).
Davide Di Bari
doaj   +1 more source

Weakly Labelled AudioSet Tagging with Attention Neural Networks

, 2019
Audio tagging is the task of predicting the presence or absence of sound classes within an audio clip. Previous work in audio tagging focused on relatively small datasets limited to recognising a small number of sound classes.
Iqbal, Turab, Kong, Qiuqiang, Plumbley, Mark D., Wang, Wenwu, Xu, Yong, Yu, Changsong   +5 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

What can we learn from Semantic Tagging?

, 2018
We investigate the effects of multi-task learning using the recently introduced task of semantic tagging. We employ semantic tagging as an auxiliary task for three different NLP tasks: part-of-speech tagging, Universal Dependency parsing, and Natural ...
Abdou, Mostafa, Abzianidze, Lasha, Bos, Johan, Kulmizev, Artur, Ravishankar, Vinit   +4 more
core   +1 more source

A Data-Driven Approach for Tag Refinement and Localization in Web Videos [PDF]

, 2015
Tagging of visual content is becoming more and more widespread as web-based services and social networks have popularized tagging functionalities among their users. These user-generated tags are used to ease browsing and exploration of media collections,
Ballan, Lamberto, Bertini, Marco, Del Bimbo, Alberto, Serra, Giuseppe   +3 more
core   +4 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source