Results 41 to 50 of about 740 (167)

Clinical Insights into the Management of Blastic Plasmacytoid Dendritic Cell Neoplasm

open access: yesCancer Management and Research, 2022
Yumeng Zhang,1,2 Lubomir Sokol2 1Department of Internal Medicine, University of South Florida, Tampa, FL, USA; 2Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL, USACorrespondence: Yumeng Zhang; Lubomir Sokol, Email yumeng.zhang ...
Zhang Y, Sokol L
doaj  

DESAFIOS E LIMITAÇÕES NO MANEJO DA NEOPLASIA DE CÉLULAS DENDRITICAS PLASMOCITÓIDES BLÁSTICAS (NCDPB): RELATO DE CASO

open access: yesHematology, Transfusion and Cell Therapy, 2023
Introdução/Objetivos: A NCDPB é uma doença rara, com comportamento agressivo e prognóstico sombrio, perfazendo menos de 0,5% de todas as neoplasias hematológicas. O trabalho visa expor o relato de caso sobre a mesma, com os desafios e limitações impostas
JPS Siqueira   +9 more
doaj   +1 more source

CD123 and More: How to Target the Cell Surface of Blastic Plasmacytoid Dendritic Cell Neoplasm

open access: yes, 2022
SIMPLE SUMMARY: Until recently, there were no approved therapies for the aggressive blood cancer blastic plasmacytoid dendritic cell neoplasm (BPDCN). Survival for patients diagnosed with BPDCN is under two years, and improved treatments are needed.
Naveen Pemmaraju   +9 more
core   +1 more source

Care Optimization for Patients With Blastic Plasmacytoid Dendritic Cell Neoplasm Receiving Tagraxofusp. [PDF]

open access: yesJ Adv Pract Oncol
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an aggressive, orphan hematologic malignancy that expresses CD123 and frequently presents in skin, bone marrow, blood, and viscera. Tagraxofusp is a first-in-class CD123-targeted therapy and the only US-approved drug to treat BPDCN.
Faysman K   +7 more
europepmc   +3 more sources

Blast and Bursts: Unveiling Splenic Rupture in Blastic Plasmacytoid Dendritic Cell Neoplasia. [PDF]

open access: yesJ Community Hosp Intern Med Perspect
Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) is a rare hematologic cancer, accounting for less than 1% of acute leukemias in the U.S. Diagnosis involves detecting markers like CD123, CD4, CD56, TCL1, and TCF4.
Hassan A   +6 more
europepmc   +2 more sources

Tagraxofusp for the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN): A Brief Report on Emerging Data

open access: yes, 2020
International audienceBlastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare myeloid malignancy, for which conventional chemotherapy has poor outcomes.
Beziat, Guillaume, Ysebaert, Loïc
core   +1 more source

Pseudomonas Exotoxin-Based Immunotoxins: Over Three Decades of Efforts on Targeting Cancer Cells With the Toxin

open access: yesFrontiers in Oncology, 2021
Cancer is one of the prominent causes of death worldwide. Despite the existence of various modalities for cancer treatment, many types of cancer remain uncured or develop resistance to therapeutic strategies.
Seyed Mehdi Havaei   +2 more
doaj   +1 more source

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) in an Elderly Female: A Rare Rash

open access: yes, 2023
Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) is a rare hematologic malignancy derived from type 2 Dendritic cells (immature Plasmacytoid dendritic cells).
Charmee Vyas   +9 more
core   +1 more source

Long-Term Benefits of Tagraxofusp for Patients With Blastic Plasmacytoid Dendritic Cell Neoplasm

open access: yesJournal of Clinical Oncology, 2022
Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary end point, may be published when key planned co-primary or secondary analyses are not yet available. Clinical Trial Updates provide an opportunity to disseminate additional results from studies, published in JCO or ...
Naveen Pemmaraju   +12 more
openaire   +2 more sources

Recent developments in the treatment of blastic plasmacytoid dendritic cell neoplasm

open access: yesTherapeutic Advances in Hematology, 2019
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a clinically aggressive hematologic malignancy derived from precursors of dendritic cells and involves most frequently the skin, bone marrow and lymph nodes. Diagnosis depends upon identification of
Minas P. Economides   +2 more
doaj   +1 more source

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