Results 101 to 110 of about 1,343,672 (294)
Gaussian Tests of "Extremal White Noise" for Dependent, Heterogeneous, Heavy Tailed Strochastic Processes with an Application [PDF]
We develop a non-parametric test of tail-specific extremal serial dependence for possibly heavy-tailed time series. The test statistic is asymptotically chi-squared under a null of "extremal white noise", as long as extremes of the time series are Near ...
Jonathan B. Hill
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Wave tails in time-dependent backgrounds [PDF]
Physical Review D, 2002 It is well-known that waves propagating under the influence of a scattering potential develop ``tails''. However, the study of late-time tails has so far been restricted to time-independent backgrounds. In this paper we explore the late-time evolution of spherical waves propagating under the influence of a {\it time-dependent} scattering potential.
openaire +2 more sources
Extremal dependence in European capital markets [PDF]
For a sample of six countries with dirty/free float regimes over 1999-2002––the United States, Japan, the Czech Republic, Poland, Switzerland, and the United Kingdom, we investigate whether paired currencies exhibit a pattern of asymptotic dependence on ...
Viviana Fernández
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
New MeditWe use multivariate copula models to assess the asymmetries in tail dependence between agricultural commodity prices (i.e., cereals and meats) and production input prices (i.e., fertilizers, seeds, animal feed and energy).
Andreas Rokopanos +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Multivariate tail dependence: further insights with an application to the Spanish banking sector
Dependence ModelingExtending bivariate dependence concepts to higher dimensions is a challenging but essential task for a comprehensive understanding of multivariate dependence.
Durante Fabrizio +3 more
doaj +1 more source
Tail behavior of a sum of two dependent and heavy-tailed distributions
Journal of Statistics and Management Systems, 2018 We consider the problem of a sum of two dependent and heavy tailed distributions through the C-convolution.
openaire +4 more sources