Results 141 to 150 of about 387,967 (213)

Targeting Microglial HDAC5 Suppresses NLRP3 Inflammation via NF‐κB Deacetylation to Alleviate Ischemic Brain Injury

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Cerebral ischemia/reperfusion induced HDAC5 upregulation in microglia. Elevated HDAC5 promoted NLRP3‐mediated neuroinflammation via NF‐κB p65 deacetylation. RGD‐EV:miR‐9‐5p delivery suppressed microglial HDAC5 and attenuated ischemic brain injury. ABSTRACT Objective Histone deacetylases are implicated in ischemic stroke, yet the role of HDAC5 remains ...
Ru‐Yu Liang, Jia‐Qi Zhang, Tian‐Yi Jiang, Li‐Qing Tao, Wen She, Zhou‐Na Sun, Cui Qi, Jun Gao   +7 more
wiley   +1 more source

Protocol for non-invasive genotyping of axolotls using skin swabbing. [PDF]

STAR Protoc
Arbanas LI, Rodrigo Albors A.
europepmc   +1 more source

Predicting Relevant Microglia‐Associated Cell–Cell Communication Pathways in Alzheimer's Disease: A Role for SPP1

Glia, Volume 74, Issue 10, October 2026.
We used CellChat to infer altered cell–cell communication in Alzheimer's disease Microglia signal to each other via SPP1 in Alzheimer's disease. SPP1‐expressing microglia are present around amyloid‐β plaques. ABSTRACT Microglia play a key role in the pathophysiology of Alzheimer's Disease (AD) and their increased heterogeneity likely affects disease ...
Janssen M. Kotah, Marina Trombetta Lima, Esmée C. Dragt, Asimenia Voulgaroglou, Nieske Brouwer, Inge R. Holtman, Susanne M. Kooistra, Bart J. L. Eggen   +7 more
wiley   +1 more source

Neural Flux-Domain Encoder Resilient to Rotor Eccentricity in BLDC Drives. [PDF]

Sensors (Basel)
Milanowski H, Piłat AK.
europepmc   +1 more source

Extracellular Vesicle‐Bound Bacterial Toxin Pneumolysin Triggers Membrane Engagement and Damage Beyond Canonical Pore Formation

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
Bacterial toxin hijacks host microvesicles to breach cell membranes Microvesicles derived from challenged host cells carrying the pneumococcal pore‐forming toxin pneumolysin promote fusion with target cells and membrane permeabilisation. Our integrated experimental and computational study reveals a mechanism by which PLY‐lipid interactions enable ...
Aswathy C. Sagilkumar, Avinashi Lal Kushwaha, Anushka Shitut, Dheeraj Kumar Sarkar, Sruthika Sukumar, Subhajit Mahanty, Somnath Dutta, Jagannath Mondal, Karthik Subramanian   +8 more
wiley   +1 more source

Balanced Adaptive Logit-Compensated Cross-Entropy and Quadratic Convolutional Network for Intelligent Fault Diagnosis Under Long-Tailed Data Distribution. [PDF]

Entropy (Basel)
Zhang W, Cao Z, Wu H, Guo D, Pu Y.
europepmc   +1 more source

Natural Killer Cell‐Derived Extracellular Vesicle Preparations Demonstrate Potent Antitumor Activity Against Human Glioblastoma In Vitro and In Vivo

Journal of Extracellular Biology, Volume 5, Issue 10, October 2026.
Schematic overview of NK‐EV isolation strategies from expanded primary human NK cells. Primary human NK cells were isolated from PBMCs and expanded using K562 feeder cells. EV‐containing preparations were then isolated from expanded NK‐cell cultures using two approaches. First, total exosome isolation reagent was used as a precipitation‐based method to
Huy Phuoc Quang Nguyen, Meesun Yoon, Shin Jung, Duck Cho, Byong Seung Cho, Tung Nguyen Thanh Uong, Jae‐Uk Jeong, Yong‐Hyub Kim, Nhat Phuoc Nguong Minh Nguyen, Tien Luyen Vu   +9 more
wiley   +1 more source

Design and Validation of a New Tilting Rotor VTOL Drone: Structural Optimization, Flight Dynamics, and PID Control. [PDF]

Sensors (Basel)
Gong H, He W, Hou S, Chen M, Yang Z, Si Q, Zhao D.   +6 more
europepmc   +1 more source

1H HR‐MAS NMR Metabolomics in Combination With Transcriptomic Correlation Provides New Insights Into Metabolic Heterogeneity Across Breast Cancer Immunohistochemical Subtypes

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Metabolomic profiling of breast cancer tissue using 1H HR‐MAS NMR spectroscopy and LCModel‐based quantitative analysis revealed metabolite differences associated with immunohistochemical subtypes, and subsequent metabolomics–transcriptomics integration linked these subtype‐dependent metabolic signatures to pathways in choline metabolism, one‐carbon ...
Irene Garcia‐Bocanegra, Jesus David Urbano‐Gamez, Antonio Perez‐Cardona, Laura Barrios, Maria Isabel Somoza‐Ramírez, Luis Vicioso, Elena Pardo‐Susacasa, Gema Diaz‐Cordoba, Maria Mercedes Acebal‐Blanco, Francisco Sendra‐Portero, Maria Luisa Garcia‐Martin   +10 more
wiley   +1 more source

Non-Intrusive Early Insulation Fault Detection for Induction Motors Using a Dual-Frequency Microstrip Antenna Array Based on UHF Partial Discharge Electromagnetic Wave Detection. [PDF]

Sensors (Basel)
Xu Y, Wu Y.
europepmc   +1 more source