Results 141 to 150 of about 22,232 (271)
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Guanylate cyclase‐C (GC‐C) is the receptor for endogenous (uro)guanylin peptides, bacterial toxins and pharmacological analogues. Receptor activation leads to intestinal fluid loss, but also activates an antiproliferative pathway and is a promising target in colorectal cancer therapy.
Renjie Xiu +4 more
wiley +1 more source
The FEBS Journal, EarlyView.The eukaryote‐specific N‐terminal domain (NTD) of eS31 uses two distinct strategies to maintain translation fidelity. During elongation, a positively charged “hotspot” fine‐tunes the selection of incoming aa‐tRNA. During termination, the entire NTD acts as a structural scaffold to ensure the correct positioning of the release factor eRF1.
Qingxuan Gao +3 more
wiley +1 more source
Damage and Failure of Aeroengine Blades Under Small UAV Impacts
International Journal of Aerospace EngineeringUnmanned aerial vehicles (UAVs) may collide with vulnerable parts of other aircrafts, such as engine blades, causing accidents. The research on small UAV impact is limited. Besides, UAV impact with propeller and rotor blades is poorly understood. In this
Zhibin Wu +3 more
doaj +1 more source
In-Flight Array Measurements of Tail Rotor Harmonic Noise [PDF]
, 2008 Acoustic data that utilized a unique flying microphone boom array was analyzed using a time domain averaging technique, based on a theoretical tail rotor one-per-rev signal, to obtain tail rotor acoustic time histories for forward and descending flight ...
Sargent, Daniel Caleb
core
S‐Adenosylmethionine (SAM) hydrolases counter increased SAM epimerisation in thermophilic archaea
The FEBS Journal, EarlyView.S‐Adenosyl‐l‐methionine (SAM) is a vital enzyme cofactor. Epimerisation at the sulfonium centre of biologically active (SS,SCα)‐SAM is driven by heat, yielding biologically inactive (RS,SCα)‐SAM. Here, two novel archaeal SAM hydrolases from the thermophilic Sulfolobus acidocaldarius and the halophilic Haloferax volcanii are shown to cleave (RS,SCα)‐SAM.
Agnes Bartels +7 more
wiley +1 more source
Advanced Engineering Research, 2011 The issues related to the quality and service properties maintain of long formed components of the tail rotor spar as an example, are considered. Vibroimpact hardening treatment technological schemes, which application will provide loss in value of the ...
Nikolay S. Koval, Peter D. Motrenko
doaj
The FEBS Journal, EarlyView.Trim32 regulates the transition from proliferation to differentiation in C2C12 cells after myogenic induction. We found that, at the onset of differentiation, Trim32 destabilizes c‐Myc mRNA, promotes cell cycle exit, and enables normal myotube formation.
Lu Xiong +6 more
wiley +1 more source
Вестник Донского государственного технического университета, 2018 The issues related to the quality and service properties maintain of long formed components of the tail rotor spar as an example, are considered. Vibroimpact hardening treatment technological schemes, which application will provide loss in value of the ...
Nikolay S. Koval, Peter D. Motrenko
doaj
CHANCE: A FRENCH-GERMAN HELICOPTER CFD-PROJECT [PDF]
, 2006 The paper gives an overview of the CHANCE research project (partly supported by the French DPAC and DGA and the German BMWA) which was started in 1998 between the German and French Aerospace Research Centres DLR and ONERA, the University of Stuttgart and
Pahlke, Klausdieter +4 more
core
Insect Molecular Biology, EarlyView.Aedes aegypti females were significantly repelled by both volatile DEET and citronella oil in comparison to control (ethanol‐exposed) mosquitoes. Global gene expression changes were largest in the mosquito mouthparts, with notable downregulation of the three subunits comprising the mosquito CO2 receptor (Gr1, 2 and 3).
Ivan Drahun +3 more
wiley +1 more source