Results 161 to 170 of about 22,232 (271)

Metabolic Assessment in Human Pluripotent Stem Cell‐Derived Cerebral Organoids Using HR‐MAS NMR Spectroscopy

open access: yesNMR in Biomedicine, Volume 39, Issue 8, August 2026.
We present a direct method for evaluating metabolism in intact hPSC‐derived cerebral organoids (COs) via HR‐MAS 1H‐NMR spectroscopy. This approach suggests that COs exhibit a metabolic profile similar to in vivo human fetal brain, with high levels of lactate and hTau, low levels of NAA, and equimolar levels of Glu and Gln.
Maria Alejandra Castilla Bolanos   +9 more
wiley   +1 more source

Flight Performance Of Multi-rotor Configuration Tail Rotors [PDF]

open access: yes
To better understand and predict the flight performance of multi-rotor configurations of tail rotors controlled via collective pitch or rotor speed, a flight performance tool is derived.
Barakos, George, Wan, Haoyun, Han, Dong
core  

A Myocyte‐Enriched Long Non‐Coding RNA NRMLncR Enhances Myogenesis in Mouse

open access: yesThe FASEB Journal, Volume 40, Issue 13, 15 July 2026.
We identified a novel myocyte‐enriched, Notch‐repressed myogenic lncRNA, NRMLncR, that is induced by myogenic regulatory factors (MRFs) during myogenic progression in mouse. NRMLncR localizes to cytoplasmic and nuclear compartments, associates with the RNA‐binding protein CUGBP Elav‐like family member 1 (CELF1), and is linked to neighboring gene Tbx1 ...
Yufen Li   +12 more
wiley   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

open access: yesAdvanced Science, Volume 13, Issue 37, 3 July 2026.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon   +21 more
wiley   +1 more source

Sensitivity of Risk‐Based Demand Curves to Analytical Fragility Function Fitting Using Multiple‐Stripe Analyses

open access: yesEarthquake Engineering &Structural Dynamics, Volume 55, Issue 9, Page 2121-2128, 25 July 2026.
ABSTRACT Risk‐based seismic assessments using demand curves that provide mean annual exceedance rates for various system demand levels are increasingly being adopted. Such assessments combine the seismic hazard curve with fragility functions for each demand level, serving as a basis to quantify the average annual losses from system damage. Constructing
Zeyad Khalil   +2 more
wiley   +1 more source

Interactions of Plant Protein and Natural Colorant: A Structural and Functional Relationship of Broccoli Protein and Marigold Color Compounds

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
Graphical representation of the interactions of the structural and functional relationships of broccoli flower protein (BFP) and marigold color compounds (MCC). This research examines BFP–MCC interactions of extracted marigold color, chemical composition, and functional attributes.
Fidele Benimana   +2 more
wiley   +1 more source

Structural basis of ligand selectivity in FAD/NAD(P)H‐dependent dehydrogenases: insights from trypanothione reductase and type II NADH dehydrogenase

open access: yesProtein Science, Volume 35, Issue 7, July 2026.
Abstract FAD/NAD(P)H‐dependent dehydrogenases form a structurally conserved family of redox enzymes that participate in essential metabolic processes across parasites and higher organisms. Among them, trypanothione reductase (TR) is a key component of the redox metabolism of Leishmania species and represents an attractive target for antileishmanial ...
Giulia Chiara Maria Perrone   +15 more
wiley   +1 more source

Microstructure Engineering Toward High Cost‐Effective Nd–Fe–B Sintered Magnets: A Review

open access: yesRare Metals, Volume 45, Issue 7, July 2026.
ABSTRACT Nd–Fe–B sintered magnets, critical for enhancing electromechanical conversion efficiency and operational stability in wind turbines and electric vehicle drives, are prized for their outstanding coercivity, high remanence, and superior maximum energy product.
Dongmin Zhang   +5 more
wiley   +1 more source

Crataegus oxyacantha Extract Enhances Cardiac Adaptation and Reduces Oxidative‐Inflammatory Stress in Broiler Chickens Raised at High Altitude Under Cold Stress

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Crataegus oxyacantha extract at 0.4 mL/L improved cardiac function in broilers under cold stress and high altitude by increasing nitric oxide synthase gene expression, boosting nitric oxide, reducing endothelin‐1 gene expression, and lowering oxidative‐inflammatory stress, offering a natural solution to mitigate pulmonary hypertension syndrome ...
Behnam Ahmadipour   +3 more
wiley   +1 more source

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