Results 31 to 40 of about 63,753 (279)

RNA‐Micelles as Self‐Assembling Structures for Efficient Co‐Delivery of Synergistic siRNA and Nucleoside Analogues to Treat CRC Lung Metastasis

open access: yesAdvanced Functional Materials, EarlyView.
Two kinds of self‐assembled RNA micelles were used to co‐deliver synergistic siRNA and nucleoside analogues for the treatment of colorectal cancer lung metastases. Near‐complete elimination of lung cancer metastases was confirmed in an orthotopic lung metastasis model constructed using human colorectal cancer lung metastases patient surgical samples to
Kai Jin   +4 more
wiley   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji   +7 more
wiley   +1 more source

Macrophage Membrane‐Cloaked, ROS‐Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome

open access: yesAdvanced Healthcare Materials, EarlyView.
The synthesis process of MM@PCD@QNPs and its potential mechanism for treating PCOS. (A) Assembly steps of MM@PCD@QNPs. (B) Synthesis and decomposition of MM@PCD@QNPs. (C) Potential therapeutic mechanisms of MM@PCD@QNPs for PCOS. PCD, PABP conjugated with DEX polymer; QUR, quercetin; CDI, N, N′‐carbonyldiimidazole; DEX, dextran; PABP, 4‐(hydroxymethyl ...
Wenzhu Li   +9 more
wiley   +1 more source

RESULTS OF THE FIRST MI-171A2 FLYING LABORATORY TEST PHASE

open access: yesНаучный вестник МГТУ ГА, 2014
The present publication describes the results of the first stage of the flying laboratory (Mi-171 helicopter) flight tests performed at Mil Moscow Helicopter Plant, JSC facilities. Main rotor components with blades made of polymer composite materials and
V. A. Ivchin, K. Y. Samsonov
doaj   +1 more source

Safe and Localized Lentiviral Gene Delivery via Injectable Mesoporous Scaffolds for Potent Antitumor Immunity

open access: yesAdvanced Materials, EarlyView.
This work introduces an injectable mesoporous silica rod scaffold that confines lentiviral vectors to the injection site, enabling localized dendritic cell recruitment and transduction. The platform sustains antigen expression, promotes robust T‐cell activation, and enhances antitumor immunity.
Thanh Loc Nguyen   +12 more
wiley   +1 more source

Design of Unmanned Helicopter Distributed Electric Tail Rotor Controller Based on Improved Active Disturbance Rejection Control

open access: yesIEEE Access
In response to the critical implications of single tail rotor failures in unmanned helicopters, this study proposes a distributed electric tail rotor yaw channel controller that employs Active Disturbance Rejection Control (ADRC) techniques.
Qing-Xin Zhang   +4 more
doaj   +1 more source

Mathematical Modeling and Stability Analysis of Tiltrotor Aircraft

open access: yesDrones, 2022
The key problem in the development process of a tiltrotor is its mathematical modeling. Regarding that, this paper proposes a dividing modeling method which divides a tiltrotor into five parts (rotor, wing, fuselage, horizontal tail, and vertical fin ...
Hanlin Sheng, Chen Zhang, Yulong Xiang
doaj   +1 more source

Aeroacoustic analysis of main rotor-tail rotor interaction [PDF]

open access: yes, 2008
The increased restrictions placed on helicopter noise levels over recent decades have encouraged manufacturers to better understand tail rotor noise and its aerodynamic sources. A generic single main rotor and tail rotor helicopter has been simulated in high speed forward, and quartering, flight using the Vorticity Transport Model.
Fletcher, Timothy M.   +2 more
openaire  

Structural Color Inkjet Printing With Mie‐Resonant Silicon Nanoparticles

open access: yesAdvanced Materials, EarlyView.
Water‐based inks incorporating Mie‐resonant silicon nanoparticles were developed, and their application to structural color inkjet printing was demonstrated. By controlling the nanoparticle size and concentration, coloration covering a wide color gamut was achieved.
Hiroto Yamana   +3 more
wiley   +1 more source

Theoretical Analysis and Experimental Researches regarding the Asymmetrical Fluid Flow Applied in Aeronautics

open access: yesAdvances in Materials Science and Engineering, 2015
The current paper has been written in order to find the best solutions to replace the antitorque rotor of single-rotor helicopters, with removal of its disadvantages through the Coandă Effect. This would significantly increase the flight performance. The
Ionică Cîrciu   +4 more
doaj   +1 more source

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