Results 11 to 20 of about 3,173 (204)

Incidence of cancer and related deaths in hemoglobinopathies: A follow-up of 4631 patients between 1970 and 2021. [PDF]

Cancer, 2023
Abstract Background The correlation between thalassemia and malignancies other than hepatocellular carcinoma (HCC) and the possible relationship between other hemoglobinopathies and tumor risk have been poorly evaluated. Methods Eight Italian specialized centers evaluated the incidence of malignant neoplasms in hemoglobinopathies as well as their sites
Origa R, Gianesin B, Longo F, Di Maggio R, Cassinerio E, Gamberini MR, Pinto VM, Quarta A, Casale M, La Nasa G, Caocci G, Piroddi A, Piolatto A, Di Mauro A, Romano C, Gigante A, Barella S, Maggio A, Graziadei G, Perrotta S, Forni GL.   +20 more
europepmc   +2 more sources

Thalassaemia is paradoxically associated with a reduced risk of in-hospital complications and mortality in COVID-19: Data from an international registry. [PDF]

J Cell Mol Med, 2022
Abstract Although numerous patient‐specific co‐factors have been shown to be associated with worse outcomes in COVID‐19, the prognostic value of thalassaemic syndromes in COVID‐19 patients remains poorly understood. We studied the outcomes of 137 COVID‐19 patients with a history of transfusion‐dependent thalassaemia (TDT) and transfusion independent ...
El-Battrawy I, Longo F, Núñez Gil IJ, Abumayyaleh M, Gianesin B, Estrada V, Aparisi Á, Arroyo-Espliguero R, Balocco M, Barella S, Beccaria A, Bonetti F, Casale M, De Michele E, Denotti AR, Fidone C, Fortini M, Gamberini MR, Graziadei G, Lisi R, Massa A, Marcon A, Rubinski B, Miano M, Motta I, Pinto VM, Piperno A, Mariani R, Putti MC, Quota A, Ribersani M, Marziali M, Roberti D, Rosso R, Tartaglione I, Vitucci A, Voi V, Zecca M, Romero R, Marouneld C, Fernández-Rozas I, Espejo C, Marhaeni W, Garcia Aguado M, Cappellini MD, Perrotta S, De Franceschi L, Piga A, Forni GL, Akin I.   +49 more
europepmc   +2 more sources

5613417 CO-TREATMENT OF ERYTHROID CELLS ISOLATED FROM Β039-THALASSEMIA PATIENTS WITH CRISPR-CAS9 GENE EDITING AND FETAL HEMOGLOBIN INDUCTION [PDF]

Hemasphere, 2023
HemaSphere, Volume 7, Issue S1, Page 41-41, April 2023.
M.L.P. Lipucci di Paola, L.C.C. Lucia Carmela Cosenza, C.Z. Cristina Zuccato, M.Z. Matteo Zurlo, R.G. Roberto Gambari, A.F. Alessia Finotti   +5 more
europepmc   +2 more sources

5613423 TREATMENT OF ERYTHROID PRECURSOR CELLS FROM β-THALASSEMIC PATIENTS WITH ISOXAZOLE DERIVATIVES: POTENT INDUCTION OF FETAL HEMOGLOBIN [PDF]

Hemasphere, 2023
HemaSphere, Volume 7, Issue S1, Page 17-17, April 2023.
C.Z. Cristina Zuccato, L.C.C. Lucia Carmela Cosenza, G.S. Gianni Sacchetti, R.R. Riccardo Rondanin, D.S. Daniele Simoni, M.P. Marco Prosdocimi, M.L.P. Lipucci di Paola, A.F. Alessia Finotti, R.G. Roberto Gambari, I.L. Ilaria Lampronti   +9 more
europepmc   +2 more sources

P129: NARRATING SICKLE CELL DISEASE: THE EXPERIENCES OF PATIENTS AND CARGIVERS [PDF]

Hemasphere, 2022
HemaSphere, Volume 6, Issue S1, Page 32-32, January 2022.
De Franceschi L, Galvani C, Ruffo G, Colombatti R, Graziadei G, Palazzi G, Venturelli D, Forni G, Quota A, Scopinaro A, Vindigni R, Zini M, Chesi P, Reale L.   +13 more
europepmc   +2 more sources

Talassemia β intermediária em gestante [PDF]

Revista Brasileira de Hematologia e Hemoterapia, 2008
A talassemia β e a forma considerada clinicamente a mais importante dentre as talassemias, em virtude do grau de morbidade e mortalidade, em consequencia da anemia hemolitica. O presente relato de caso refere-se a uma gestante portadora da talassemia β intermediaria, identificada em programa de rastreamento de anemia hemolitica e tem como objetivo ...
Sakamoto, Tatiana M., Peruzzo, Giselle M., Ivo, Maria Lúcia, Brum, Maria Aparecida R., Bonini-Domingos, Cláudia R.   +4 more
openaire   +6 more sources

Il racconto della talassemia: Nelle mie vene e Paura di guarire

Rhesis, 2022
Il presente studio intende analizzare il racconto della talassemia in due testi contemporanei: Paura di guarire, di Ivano Argiolas (2021), e Nelle mie vene, di Flavio Soriga (2019).
Ramona Onnis
doaj   +1 more source

Impact of the preparation method of red cell concentrates on transfusion indices in thalassemia patients: A randomized crossover clinical trial

Transfusion, Volume 61, Issue 6, Page 1729-1739, June 2021., 2021
Abstract Background The average hemoglobin content of red cell concentrates (RCC) varies depending on the method of preparation. Surprisingly less data are available concerning the clinical impact of those differences. Study Design and Methods The effects of two types of RCC (RCC‐A, RCC‐B) on transfusion regime were compared in a non‐blinded ...
Maria Rita Gamberini, Monica Fortini, Alice Stievano, Eleonora Calori, Maria Vittoria Riontino, Giovanni Ceccherelli, Donatella Venturelli, Roberta Chicchi, Rino Biguzzi, Francesco Fagnoni, Giuseppina Angela Portararo, Daniela Lasagni, Elena Borotti, Ruggero Buonocore, Maurizio Govoni, Roberto Reverberi   +15 more
wiley   +1 more source

PROTOCOLOS CLÍNICOS EM BETA-TALASSEMIA

Hematology, Transfusion and Cell Therapy, 2023
Objetivos: Este trabalho tem como objetivo realizar um levantamento estatístico sobre os principais protocolos de pesquisa clínica, utilizando o banco de dados do Clinical Trials, envolvendo terapia gênica em pacientes com beta-talassemia. Pacientes portadores de talassemias, principalmente com o quadro de beta-talassemia major, sofrem de uma ...
LAB Faria, FM Lima, JVDS Bianchi
openaire   +2 more sources

Selecting β‐thalassemia Patients for Gene Therapy: A Decision‐making Algorithm

HemaSphere, Volume 5, Issue 5, May 2021., 2021
This expert opinion originally developed by a panel of the Italian Society of Thalassemias and Hemoglobinopathies (SITE), reviewed and adopted by the European Hematology Association (EHA) through the EHA Scientific Working Group on Red Cells and Iron, has been developed as priority decision‐making algorithm on evidence and consensus with the aim to ...
Donatella Baronciani, Maddalena Casale, Lucia De Franceschi, Giovanna Graziadei, Filomena Longo, Raffaella Origa, Paolo Rigano, Valeria Pinto, Monia Marchetti, Antonia Gigante, Achille Iolascon, on behalf of & Chair of, the EHA Scientific Working Group on Red Cells and Iron, Gian Luca Forni   +13 more
wiley   +1 more source