Results 31 to 40 of about 265,258 (240)

Association of incidence of colorectal polyp with markers of insulin resistance and other related factors: a cross-sectional study

open access: yesScientific Reports
To explore the relationship between the incidence of colorectal polyps and related factors such as markers of insulin resistance (IR) ,  a retrospective analysis was used to collect 2716 patients who underwent physical examinations in Guangzhou Cadre and
Yan Xu   +8 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Towards greater visibility and recruitment of skilled refugees

open access: yesForced Migration Review, 2018
Showcasing refugees’ skills connects refugees to global work opportunities, and also shifts the narrative from one of refugees being burdens to host countries to one in which refugees are recognised as skilled workers for whom countries should be ...
Leah Nichles, Sayre Nyce
doaj  

A study on the correlation of thyroid nodules with METS-IR and SII in a population undergoing health checkups

open access: yesFrontiers in Endocrinology
ObjectiveTo investigate the associations between thyroid nodules and two emerging biomarkers-Metabolic Score for Insulin Resistance (METS-IR) and Systemic Immune-Inflammation Index (SII)-in adults undergoing routine health checkups.MethodsIn this ...
Ruoping Guan   +3 more
doaj   +1 more source

Disciplinary variations in student perceptions of active learning classrooms

open access: yesInternational Journal of Educational Research Open, 2022
The use of active learning classrooms (ALCs) has attracted considerable attention in higher education research in the past two decades. Researchers have reported the positive effects of ALCs on student learning.
Pit Ho Patrio Chiu   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Agreement Between the KTK3+ Test and the Athletic Skills Track for Classifying the Fundamental Movement Skills Proficiency of 6- to 12-Year-Old Children

open access: yesFrontiers in Education, 2021
The main aim of this study was to determine the agreement in classification between the modified KörperKoordinations Test für Kinder (KTK3+) and the Athletic Skills Track (AST) for measuring fundamental movement skill levels (FMS) in 6- to 12-year old ...
M. de Niet   +6 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Unblocking the Lifeline of Talent. CEPS Policy Brief No. 306, 6 December 2013 [PDF]

open access: yes, 2013
Against the background of looming demographic decline, the departure of the baby-boom generation from European labour markets and growing economic competitiveness from emerging economies, this CEPS Policy Brief, published jointly with the Bertelsmann ...
Busse, Mathias, Morehouse, Christal.
core  

A comparison of cemented and cementless intra-neck curved stem use during hip-preserving reconstruction following massive femoral malignant tumor removal

open access: yesFrontiers in Oncology, 2022
BackgroundPatients who undergo massive femoral malignant tumor (MFMT) resection often exhibit shortened femoral metaphyseal juxta-articular segments. The use of a customized femoral endoprosthesis (CFE) with an intra-neck curved stem (INCS) has emerged ...
Qi You   +17 more
doaj   +1 more source

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